Setyabudi Goenharto
Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.

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The effect of butterfly pea flower (Clitoria ternatea L.) kombucha solution as an antibiofilm agent against Porphyromonas gingivalis Tamara Yuanita; Naia Naurora Sabilla; Awang Bagus Firmansyah; Devi Eka Juniarti; Setyabudi Goenharto; Eric Priyo Prasetyo; Daniyal Lazuardi Ramadhan
Conservative Dentistry Journal Vol. 16 No. 1 (2026): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v16i1.2026.34-40

Abstract

Background: Porphyromonas gingivalis is one of the predominant pathogens found in 28% infected root canal cases. This bacterium is capable of forming biofilms that increase its resistance to antimicrobial agents. Sodium hypochlorite (NaOCl) 2.5% is commonly used as an endodontic irrigant due to its strong antimicrobial activity; however, it can be cytotoxic and cause periapical tissue irritation if extruded beyond the apex. Kombucha contains bioactive compounds such as flavonoids, alkaloids, tannins, saponins, and terpenoids, as well as organic acids from fermentation that may inhibit microbial growth. This study investigated the antibiofilm potential of butterfly pea kombucha against P .gingivalis. Purpose: This study aimed to evaluate the effectiveness of butterfly pea kombucha in inhibiting and eradicating P . gingivalis biofilm through the determination of MBIC₉₀ and MBEC₉₉ values. Methods: This laboratory experimental study used a post-test only control group design with nine groups: kombucha concentrations of 100–70%, positive control (NaOCl 2.5%), and negative control. Biofilm inhibition was assessed by the microtiter plate assay with crystal violet staining and optical density reading at 540 nm. Data were analyzed using One-way ANOVA and Tukey HSD (p<0.05). Results: The results showed that MBIC₉₀ was achieved at the 100% concentration, demonstrating biofilm inhibitory activity comparable to the positive control based on the Tukey HSD test (p > 0.05). Conclusion: These findings indicate that high concentration butterfly pea kombucha has potential as a natural antibiofilm agent against Porphyromonas gingivalis.
Management of post cleft lip and palate aesthetic defects with bilayered zirconia crowns - a digital approach Nurani Atikasari; Mefina Kuntjoro; Bambang Agustono; Karina Mundiratri; Harry Laksono; Agus Dahlan; Abil Kurdi; Fatimah Batul; Setyabudi Goenharto
Conservative Dentistry Journal Vol. 16 No. 1 (2026): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v16i1.2026.61-65

Abstract

Background: Soft tissue asymmetry, alveolar bone shortage, and anterior tooth loss are common presentations for patients with cleft lip and palate (CLP), which makes restorative rehabilitation more challenging. The cost-effectiveness, accuracy, and time optimisation of digital dental workflows for the production of fixed restorations or prostheses have shown them to be superior to conventional ones. In these situations, achieving both functional stability and aesthetic harmony calls for an all-encompassing, multidisciplinary strategy. Purpose: This report aims to describe the restorative and prosthodontic management of anterior tooth loss in a post-CLP patient using a bilayered zirconia fixed crowns within a fully digital workflow. Case: A 23-year-old female presented with a missing maxillary left lateral incisor (tooth 22) and a history of multiple CLP surgeries, the most recent performed in January 2023. Radiographic evaluation revealed significant alveolar bone resorption (>50%) at the edentulous site. The patient had undergone orthodontic treatment since 2017 but had not received prior restorative and prosthodontic rehabilitation. Case Management: A bilayered zirconia fixed crowns was planned to restore esthetics and function. Pre-treatment procedures included endodontic therapy on tooth 12, intraoral scanning, and diagnostic mock-up. Intraoral digital impressions enabled precise CAD/CAM fabrication. To address Class II gingival recession, 2–3 mm of gingival-colored porcelain was applied to mimic natural soft tissue. A modified ridge lap pontic was designed to optimize hygiene and achieve a lifelike emergence profile. Conclusion: Bilayered zirconia restorations, combined with a digital restorative approach, offer favorable esthetic and functional outcomes in post-CLP anterior rehabilitation.