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All Journal The Indonesian Journal of Infectious Diseases SWARNA
Stephanie Jesslyn
Master Program In Biomedical Sciences, Faculty Of Medicine, Universitas Sumatera Utara, Medan
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

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The Effect of Propolis (Bee Glue) on Sepsis: A Systematic Review Stephanie Jesslyn; Ririe Fachrina Malisie
The Indonesian Journal of Infectious Diseases Vol. 11 No. 2 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i2.408

Abstract

Background: With pathogenic resistance and risk of dysbiosis, antimicrobial therapy for sepsis becomes less effective. Therefore, there is a need for an additional therapy, such as immunomodulation, either directly or through modulation of the gut microbiota. Propolis, or bee glue, has immunomodulatory properties and positive effects on the gut microbiota. This systematic review aims to assess the potential of propolis as an adjunctive therapy in alleviating sepsis through pathways associated with gut microbiota, such as inflammation and oxidative stress. Methods: This study was made in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. The keywords for the literature search and study relevance were determined with the Population, Intervention, Comparison, and Outcome (PICO) formula: Population (P): Septic human or animal; Intervention (I): Propolis administration; Comparison (C): Septic human or animal without propolis administration; Outcome (O): Gut microbiota and inflammatory as well as oxidative stress biomarkers. A literature search was conducted in PubMed, ScienceDirect, and Google Scholar to obtain relevant studies with a download period from January 2015 to March 2025. Results: The literature search yielded 3,189 articles, with four articles eligible for inclusion in this literature review. The four studies were animal studies and reported that propolis administration improved sepsis by reducing inflammatory and oxidative stress biomarkers and mitigating organ damage. None of the studies reported the outcome on gut microbiota in sepsis. Conclusion: Propolis showed potential as an adjunctive therapy for sepsis through its anti-inflammatory and antioxidative effects, but there is no evidence from human studies.  
Edukasi Bahaya Merokok dan Gambaran Pengetahuan, Sikap, Perilaku Masyarakat tentang Pencegahan Kanker Paru di Car Free Day Kota Medan Muhammad Abdi Riyantono; Erwin Handoko; Enie Enie; Stephanie Jesslyn; Theresia Anggriani H
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 8 (2026): SWARNA : Jurnal Pengabdian Kepada Masyarakat, Agustus, 2026
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v5i8.3918

Abstract

Merokok merupakan salah satu faktor risiko utama kanker paru dan penyakit tidak menular lainnya, namun kesadaran masyarakat mengenai bahayanya masih perlu ditingkatkan. Kegiatan pengabdian kepada masyarakat ini bertujuan memberikan edukasi bahaya merokok dan memperoleh gambaran pengetahuan, sikap, dan perilaku (PSP) masyarakat tentang pencegahan kanker paru dalam rangka World No Tobacco Day di kawasan Car Free Day (CFD) Kota Medan. Metode kegiatan meliputi edukasi langsung melalui ceramah dan diskusi interaktif, dilanjutkan pengisian kuesioner PSP oleh pengunjung CFD yang bersedia menjadi responden. Sebanyak 29 responden mengisi kuesioner secara lengkap. Hasil menunjukkan rata-rata skor pengetahuan sebesar 90,1% dan sikap sebesar 91,8%, keduanya berada pada kategori baik, sedangkan rata-rata skor perilaku sebesar 76,4% dengan variasi yang lebih besar, hanya 31,0% responden yang rutin beraktivitas fisik dan 48,3% yang mengonsumsi buah-sayur setiap hari. Kesenjangan antara pengetahuan/sikap yang baik dan perilaku hidup sehat yang belum optimal ini menunjukkan perlunya penguatan intervensi perubahan perilaku secara berkelanjutan, tidak hanya edukasi satu arah.
Co-Authors Enie Enie Erwin Handoko Muhammad Abdi Riyantono Ririe Fachrina Malisie Theresia Anggriani H