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All Journal Eduvest - Journal of Universal Studies
I Wayan Gede Artawan Eka Putra
Universitas Udayana, Indonesia
Aerospace Engineering Computer Science & IT Health Professions Neuroscience Social Sciences

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The Relationship Between Brainstem Structural Anatomical Parameters And Cognitive Function Impairment Based On The Indonesian Version Of Montreal Cognitive Assessment Score In Clinical Dementia Patients Ivola Lita Widodo; Firman Parulian Sitanggang; I Made Dwijaputra Ayusta; I Wayan Gede Artawan Eka Putra
Eduvest - Journal of Universal Studies Vol. 5 No. 8 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i8.52021

Abstract

Dementia is a neurodegenerative disorder characterized by a significant decline in cognitive function. Some studies suggest that structural changes in the brainstem can contribute to cognitive impairment. However, the relationship between the structural anatomical parameters of the brainstem and cognitive function impairment based on the Indonesian version of the Montreal Cognitive Assessment (MoCA) Score in patients with clinical dementia is still not widely studied. This study is an analytical observational study involving 65 patients with clinical dementia who underwent a head MRI examination at Ngoerah Hospital, Denpasar, Bali. The analyzed brainstem structural anatomical parameters included the diameter of the midbrain anteroposterior (AP), midbrain-to-pons ratio, superior cerebellar peduncle (SCP) width, middle cerebellar peduncle (MCP) width, and interpeduncular angle. The relationship between these parameters and cognitive function was measured using the MoCA-Ina score and analyzed by correlation and logistic regression tests. The average diameter of the AP midbrain was 11.1 cm (± 1.63 cm), the median midbrain-to-pons ratio was 0.19, and the median width of SCP and MCP was 1.8 cm and 7.9 cm, respectively. The results of the analysis showed that there was a sufficient positive relationship between the diameter of the AP midbrain and the midbrain-to-pons ratio (r = 0.329, p < 0.001) and between the width of SCP and MCP and the midbrain-to-pons ratio (r = 0.432 and 0.279, p < 0.001). The midbrain-to-pons ratio and MCP width were significantly related to the MoCA-Ina score (r = 0.265 and 0.447, p < 0.001).
The Relationship Between Subcutaneous and Visceral Fat Thickness and Osteoporosis Incidence in Women Aged ≥50 Years At Rsup Prof. Dr. I.G.N.G. Ngoerah Made Surya Saptono Putra; Elysanti Dwi Martadiani; I Made Dwijaputra Ayusta; I Wayan Gede Artawan Eka Putra
Eduvest - Journal of Universal Studies Vol. 5 No. 11 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i11.52208

Abstract

Osteoporosis adalah penyakit yang ditandai dengan penurunan massa dan kualitas mikroarsitektur tulang, serta peningkatan risiko patah tulang, terutama pada wanita lanjut usia. Wanita lebih rentan terhadap osteoporosis karena faktor hormonal dan fisiologis. Penelitian ini bertujuan mengevaluasi hubungan ketebalan lemak subkutan dan visceral dengan kejadian osteoporosis pada wanita ≥50 tahun. Penelitian observasional dengan desain potong lintang ini melibatkan 39 wanita yang menjalani pemeriksaan DXA di RSUP Prof. Dr. I.G.N.G. Ngoerah pada Januari–Februari 2025. Ketebalan lemak diukur menggunakan ultrasonografi, dan diagnosis osteoporosis berdasarkan T-score DXA. Hasil analisis menunjukkan ketebalan lemak subkutan abdomen ≥23,5 mm (OR 19,0, p < 0,01) dan lemak visceral abdomen ≥10,2 mm (OR 76,0, p < 0,01) berhubungan dengan peningkatan risiko osteoporosis. Ketebalan lemak subkutan paha ≥10,5 mm (OR 4,5, p = 0,041) dan dorsal ≥14,5 mm (OR 10,6, p = 0,003) juga menunjukkan hubungan signifikan. Analisis regresi logistik menunjukkan ketebalan lemak subkutan abdomen ≥23,5 mm (aOR 5,1, p = 0,008) dan lemak visceral abdomen ≥10,2 mm (aOR 12,2, p = 0,002) sebagai determinan risiko osteoporosis yang signifikan. Penelitian ini menunjukkan pentingnya penilaian ketebalan lemak, khususnya lemak visceral, dalam mengidentifikasi risiko osteoporosis pada wanita lanjut usia.
Co-Authors Elysanti Dwi Martadiani Firman Parulian Sitanggang I Made Dwijaputra Ayusta Ivola Lita Widodo Made Surya Saptono Putra