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All Journal JOPS (Journal Of Pharmacy and Science)
Dwi Retno Sari
STIKes KHAS Kempek Cirebon
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Utilization of Methanol Extract Sea Pandan Fruit (Pandanus tectorius) in Hand and Body Cream as an Antioxidants Dwi Retno Sari; Yusfia Urwatul Wutsqa; Siti Nur Hikmah
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.4706

Abstract

Sea pandanus is a coastal plant with great potential in the cosmetic industry due to its rich contains phenolic and flavonoid compounds that are abundant in the fruits. The purpose of this research is determine the antioxidant activity of sea pandanus fruit and to evaluate the result of hand and body cream formulation. Pandanus was chosen because it is not widely explored.The result of study showed that the methanol extract of sea pandanus contains phenolic, flavonoid, saponin, and steroid compounds. The antioxidant activity in the hand and body cream formulation was 33,183 µg/mL, indicating strong antioxidant activity below the IC50. The high level antioxidant activity from the methanol extract of sea pandanus can be used in the formulation of hand and body cream. Characteristics in the quality assessment of all the hand and body cream did not meet the requirements.
Formulasi dan Uji Antibakteri Staphylococcus aureus Terhadap Sediaan Sabun Kertas Ekstrak Serai Dapur (Cymbopogon citratus) Dwi Retno Sari; Eno Mahmudah; Yusfia Urwatul Wutsqa
JURNAL FARMASI DAN MAKANAN Vol 8 No 1 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i1.5456

Abstract

Paper soap is a unique soap that has a thin sheet shape similar to paper. Citratus or also known as lemongrass is a well-known herbal medicine with a myriad of benefits. This study aims to evaluate the ethanol extract of lemongrass (Cymbopogon citratus Dc) as an ingredient in making paper soap. Lemongrass is known to contain various compounds such as saponins, flavonoids, and essential oils, which have the potential to inhibit bacterial growth. The experimental method was used to make paper soap from lemongrass extract with formulations I, II, and III with a percentage of 5%, 10% and 15% lemongrass extract. Then the evaluation and test of antibacterial effectiveness against staphylococcus aureus using the paper disc diffusion method. Organoleptic tests showed that the color and aroma of the soap became more intense with increasing extract concentration. The pH test revealed that the soap had a pH range of 6-11, suitable for soap. The foam height test showed all formulas, except the third, met the standard. The antibacterial test showed that the zone of inhibition of Staphylococcus aureus increased as the concentration of lemongrass extract increased. Formulations with 5%, 10%, and 15% percentages formed inhibition of 21.35 mm, 23.52 mm, and 26.6 mm, respectively. These results indicate that formulations containing higher lemongrass extract have relatively better antibacterial ability.
Skrining Fitokimia Ekstrak Herba Serai Wangi (Cymbopogon nardus) Variasi Pelarut dan Stabilitas Lotion Repellent Nyamuk Dwi Retno Sari; Moh Mukhlishin; Fawwaz Muhammad Fauzi
JURNAL FARMASI DAN MAKANAN Vol 8 No 1 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i1.5457

Abstract

Dengue Hemorrhagic Fever (DHF) is a health problem in Indonesia. Until the 22nd week of 2024, there were 119,709 dengue cases with 777 deaths. The use of citronella (Cymbopogon nardus) repellent is done to prevent it. This study aims to determine the content of citronella extract with ethanol (polar), ethyl acetate (semi-polar), and n-hexane (non-polar) solvents as active ingredients of mosquito repellent lotion and determine the stability of the lotion. The type of this research is experimental research with true experimental design:the posttest-only control group design. Phytochemical screening was conducted to determine the saponin, flavonoid, alkaloid, phenolic, triterpenoid, and steroid content of each extract. Lotion stability is tested for 28 days by storing the lotion at room temperature. On days 0, 14, and 28, the organoleptic, homogeneity, pH, adhesion, spreadability, and emulsion type tests were carried out on the lotion. The results of phytochemical screening showed that the ethanol extract contains saponins, flavanoids, and phenolics. The ethyl acetate extract contains steroid. The n-hexane extract contains triterpenoid and steroid. The results of the stability test showed that all preparations met the requirements of the organoleptic test, homogeneity test, pH test, adhesion test, and emulsion type test which are good and stable. But it does not meet the requirements of a good spreadability test.
Co-Authors Eno Mahmudah Fawwaz Muhammad Fauzi Moh Mukhlishin Siti Nur Hikmah Yusfia Urwatul Wutsqa Yusfia Urwatul Wutsqa