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All Journal Klinikal Sains (Jurnal Analis Kesehatan) Jurnal Sehat Mandiri
Nurul Amalia
Universitas Borneo Lestari
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Public Health

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HUBUNGAN DISLIPIDEMIA DAN DIABETES MELITUS TIPE 2 DITINJAU DARI KOLESTEROL & TRIGLISERIDA DI RSDI BANJARBARU : HUBUNGAN DISLIPIDEMIA DAN DIABETES MELITUS TIPE 2 DITINJAU DARI KOLESTEROL & TRIGLISERIDA DI RSDI BANJARBARU Rizka Ayu Wahyuni; Aulia Syafa Al Fitri; Nurbidayah Nurbidayah; Nurul Amalia; Noor Zahwa Mubarakah
Klinikal Sains : Jurnal Analis Kesehatan Vol. 14 No. 1 (2026): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v14i1.8049

Abstract

Type 2 Diabetes Mellitus is one of the non-communicable diseases with an increasing prevalence and a major contribution to cardiovascular complications. Insulin resistance in Type 2 Diabetes Mellitus not only causes hyperglycemia but may also affect lipid metabolism, potentially leading to dyslipidemia. This study aimed to determine the relationship between blood glucose levels and total cholesterol and triglyceride levels in patients with Type 2 Diabetes Mellitus. This research used an analytic design with a cross-sectional approach involving 45 patients with Type 2 Diabetes Mellitus who underwent lipid profile examination at the Clinical Pathology Laboratory of RSDI Banjarbaru. Data were analyzed using the Chi-Square test to assess the association between variables. The results showed that there was no significant relationship between blood glucose levels and total cholesterol levels or triglyceride levels (p > 0.05). Increased blood glucose levels were not statistically associated with elevated lipid levels in patients with Type 2 Diabetes Mellitus.
Perbandingan Jumlah Leukosit Menggunakan Ekstrak Buah Limau Kuit sebagai Reagensia Alternatif Muhammad Arsyad; Nurul Amalia; Nurbidayah Nurbidayah
Jurnal Sehat Mandiri Vol 20 No 1 (2025): Jurnal Sehat Mandiri, Volume 20 Nomor 1 Juni 2025
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v20i1.1856

Abstract

Limau kuit (Citrus hystrix DC) is a fruit that has a distinctive sour taste. The sourness in limau kuit extract can be used to replace glacial acetic acid, which is one of the compounds found in reagents used to aid in the diagnosis of certain diseases. One of the reagents that contains acetic acid is Turk’s solution, which functions to stain leukocyte cells and lyse other cells except leukocytes, thus enabling leukocyte count analysis. The objective of this study was to count leukocytes using a modified Turk’s solution made from limau kuit extract and compare the results with those obtained using commercial Turk’s solution. The study design was a randomized post-test only controlled group design, using instruments such as a microscope, micropipette, test tubes, and an improved Neubauer chamber. The research was conducted in the pathology laboratory of Universitas Borneo Lestari in October 2024. Leukocyte count examinations were performed in 16 repetitions, followed by statistical data analysis using the Independent Sample T-Test. The results showed that the leukocyte counts obtained using the modified Turk’s solution from limau kuit extract did not show a significant difference. The difference in mean leukocyte count was 40.63 cells/mm³, with a median difference of 100 cells/mm³, a maximum difference of 150 cells/mm³, and a minimum difference of 200 cells/mm³. Microscopically, erythrocytes were completely lysed and leukocytes were clearly visible; however, bacterial contamination was still observed in the field of view. In conclusion, the modification of Turk’s reagent using limau kuit extract showed no significant difference between the control group (commercial Turk’s reagent) and the treatment group.
Co-Authors Aulia Syafa Al Fitri Muhammad Arsyad Noor Zahwa Mubarakah Nurbidayah Rizka Ayu Wahyuni