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All Journal Collaborative Medical Journal (CMJ)
Mahendra Mahendra
Rumah Sakit Santa Maria Pekanbaru
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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PENGARUH GEL PUTIH TELUR BEBEK TERHADAP PENYEMBUHAN LUKA INSISI PADA MENCIT (Mus musculus) Mahendra Mahendra; Abdul Karim; Arman Ismail; Lasmaria Flora Roslinda Silaen
Collaborative Medical Journal Vol 6 No 2 (2023): Mei
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v6i2.3840

Abstract

Skin injuries are a common health problem and can be caused by various factors such as injury or surgery. The skin is the body's first defense against microorganisms and chemicals, so wounds on the skin can cause damage to tissues. The prevalence of wounds in Indonesia increased from 7.5% in 2012 to 8.2% in 2013. Traditional medicine is still widely used by the people, and eggs have potential as an effective alternative treatment because they are rich in protein and amino acids needed to form new tissues and speed up the healing process. Based on searches on PubMed, there has been no research on the relationship between duck egg whites to incision wound healing. Analyze the effect of duck egg white gel on the healing of incision wounds in mice. The study was an experimental study with a Posttest only with Control Group design, involving twenty mice that were divided into four groups: a positive control group using povidone iodine, a negative control group using a gel base, and two treatment groups. The remaining length of the wound was measured every 2 days using calipers on days 3, 5, and 7. The results of the study showed a p-value of <0.05, indicating that duck egg white gel at both 10% and 20% concentrations was effective in accelerating the healing of incision wounds in mice. The duck egg white gel at a concentration of 20% exhibited the most significant effectiveness in promoting the healing of incision wounds in mice
PENGARUH GEL PUTIH TELUR BEBEK TERHADAP PENYEMBUHAN LUKA INSISI PADA MENCIT DIABETES Mahendra Mahendra; Dwi Jayanti; Riski Dwi Utami; Olvaria Misfa; May Valzon
Collaborative Medical Journal Vol 8 No 1 (2025): Januari 2025
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v8i1.5809

Abstract

The International Diabetes Federation (IDF) in 2019 stated that around 463 million people aged 20-79 years in the world suffer from diabetes mellitus. Indonesia is ranked seventh in the world suffering from diabetes mellitus. The highest wound prevalence in the world is incision wounds with a prevalence of 48%. Diabetes mellitus can inhibit the healing of incision wounds, because it increases the risk of infection due to impaired metabolic activity. Egg white is one of the traditional ingredients that can be used to heal incision wounds. In this study, duck egg white was used to see the effect of duck egg white gel on healing incision wounds in diabetic mice. This study is an experimental study with a post-test only with control group design with 16 mice divided into a positive control group, a negative control group, treatment group 1 with 10% duck egg white gel and treatment group 2 with 20% duck egg white gel. The treatment in the form of mice injected with alloxan 0.05 ml/head and incised on the back of the mouse with a length of 1 cm and a depth of 0.2 cm and the measurement of the remaining wound length using a caliper on days 3, 5, 7, and 14. Based on the One Way Anova test on days 3, 5, 7, and 14, a p value <0.05 was obtained which indicated that duck egg white gel with a concentration of 10% and 20% was effective in accelerating the healing of incision wounds in mice. Duck egg white gel with a concentration of 20% had the most adequate effectiveness in healing incision wounds in diabetic mice. Based on this study, administration of duck egg white gel with a concentration of 10% and 20% was effective in healing incision wounds in diabetic mice.
Co-Authors Abdul Karim Arman Ismail Dwi Jayanti Lasmaria Flora Roslinda Silaen May Valzon Olvaria Misfa Riski Dwi Utami