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p-Index From 2021 - 2026
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All Journal Biology, Medicine, & Natural Product Chemistry Livestock and Animal Research
Muhammad Hatta
Hasanuddin University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health Veterinary

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Biological Determinants of Memory Performance In Qur’an Memorizers: Evidence from Cathecol-O-Methyl-Transferase (COMT) Gene Expression And Protein Levels Rosdianah Rahim; Suryani As’ad; Veni Hadju; Saidah Syamsuddin; Muhammad Hatta; Nadyah Haruna; Syatirah Jalaluddin; Yessy Kurniati
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.1373-1380

Abstract

Memory performance during adolescence is a key aspect of cognitive development and is strongly influenced by dopaminergic regulation in the prefrontal cortex. Catechol-O-Methyltransferase (COMT) plays a critical role in modulating dopamine availability and cognitive function. This study examined the relationships between age, COMT gene expression, COMT protein levels, and memory performance among adolescents engaged in structured memorization activities. A quantitative cross-sectional design was applied involving male adolescent participants. Memory performance was assessed using a standardized psychometric test, while COMT gene expression and protein levels were measured using reverse transcription quantitative polymerase chain reaction and enzyme-linked immunosorbent assay, respectively. Statistical analyses included descriptive statistics and correlation tests. The results demonstrated a significant negative association between age and memory performance within the adolescent range. In contrast, COMT gene expression and protein levels showed strong positive correlations with memory performance, indicating that higher molecular regulation of dopamine was associated with superior cognitive outcomes. Memorization duration and quantity were not significantly related to memory performance. These findings support dopamine-based models of cognitive regulation and highlight the importance of molecular biomarkers in understanding adolescent memory development. The study contributes to developmental cognitive research by emphasizing biologically informed approaches and provides a foundation for future longitudinal investigations.
Performance of Bali Cattle by the Implementation of Quadruple Helix Participatory-Based Breeding Programs in Optimizing the Potential of Smallholder Cattle Farms Zulkharnaim Zulkharnaim; Syahdar Baba; Muhammad Hatta; Hikmah M. Ali
Livestock and Animal Research Vol 22, No 3 (2024): Livestock and Animal Research
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/lar.v22i3.89061

Abstract

Objective: This study aims to determine the impact of implementing a participatory-based breeding program on productivity as represented by cattle morphometric measures, technical coefficients and supporting factors among smallholder farmers in Barru District, South Sulawesi Province. Methods: The research method used 1,040 cattle recordings from 2017 to 2022 in Barru district, South Sulawesi Province, Indonesia, with the following sub-districts being included: Tanete Riaja, Tanete Rilau, Balusu, Barru, and Mallusetasi. The study employed descriptive analysis, a paired-sample T test, and an analysis of the interaction between breeding variables using the general linear model. Results: The results showed that the morphometric size of participatory-based breeding programs (PBBP) had higher CG values (p<0.01) than non-participatory breeding programs (NPBBP).. The NI PBBP value was found to be in the low category (33.82%), while the NPBBP value was found to be 6.94%. A further impact was observed, whereby male and female calves exhibited distinct differences in WH, BL and CG each year between 2020-2022, with statistical significance (p<0.01). Conclusions: This study showed that factor breeding program models (PBBP and NPBBP) significantly influenced the morphometric size (p < 0.01). The implementation of the PBBP scheme has had a positive impact, as evidenced by the application of the Quadruple Helix model.
Co-Authors Hikmah M. Ali Nadyah Haruna Rosdianah Rahim Saidah Syamsuddin Suryani As’ad Syahdar Baba Syatirah Jalaluddin Veni Hadju Yessy Kurniati Zulkharnaim Zulkharnaim