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The Role of Age and Sex in Triglyceride and Total Cholesterol Levels among Adults: Implications for Degenerative Disease Risk Yulia Ratna Dewi; Mahjanah Hussein; Yulita Maulani; Muhammad Sony Al-Jufri
Health Research Journal of Indonesia Vol 4 No 5 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i5.1100

Abstract

Penyakit degeneratif, khususnya penyakit kardiovaskular, merupakan penyebab utama morbiditas dan mortalitas yang berkaitan dengan gangguan metabolisme lipid. Faktor demografi seperti usia dan jenis kelamin diduga memengaruhi variasi kadar trigliserida dan kolesterol total. Penelitian ini bertujuan untuk menganalisis peran usia dan jenis kelamin terhadap kadar trigliserida dan kolesterol total pada populasi dewasa sebagai indikator risiko penyakit degeneratif. Penelitian ini menggunakan desain observasional analitik dengan pendekatan cross-sectional terhadap 47 subjek dewasa menggunakan data sekunder. Analisis statistik meliputi uji Mann–Whitney, uji t independen, korelasi Spearman dan Pearson, serta regresi linear berganda. Hasil penelitian menunjukkan terdapat perbedaan signifikan kadar trigliserida dan kolesterol total berdasarkan jenis kelamin (p<0,001). Terdapat hubungan positif yang kuat antara usia dengan kadar trigliserida (r=0,833; p<0,001) dan kolesterol total (r=0,844; p<0,001). Analisis regresi menunjukkan usia berpengaruh signifikan terhadap trigliserida, sedangkan usia dan jenis kelamin merupakan prediktor signifikan terhadap kolesterol total. Disimpulkan bahwa usia dan jenis kelamin berperan dalam menentukan variasi profil lipid pada dewasa, sehingga penting dalam deteksi dini risiko penyakit degeneratif.
Effectiveness of Lavender Aromatherapy Administration on Insertion Pain in Hemodialysis Patients Risma Ayu Putri Diani; Endrat Kartiko Utomo; Marni Marni; Mahjanah Hussein
OVUM : Journal of Midwifery and Health Sciences Vol. 6 No. 1 (2026): OVUM : Journal of Midwifery and Health Sciences
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/8bhwer55

Abstract

Insertion pain is a significant problem for hemodialysis patients that can reduce comfort and therapy compliance. Non-pharmacological interventions are needed. This study aims to analyze the effectiveness of lavender aromatherapy to reduce insertion pain in hemodialysis patients at RSUD Ir. Soekarno Sukoharjo. This study method is a randomized controlled trial with a pretest-posttest control group design. The sample consisted of 40 respondents selected through purposive sampling and divided into intervention groups (n=20) and control groups (n=20). The intervention group received lavender aromatherapy inhalation for 5-10 minutes before insertion. The pain scale was measured using the Wilcoxon and Mann-Whitney tests. The results showed that before the intervention, the average pain score of both groups was in the moderate category (intervention=4.45, control=4.35). After the intervention, the pain score of the intervention group decreased significantly to 2.55 (mild pain), while the control group remained at 4.40 (moderate pain). Statistical tests showed a very significant difference between the groups (p=0.000). Cohen's results (2.44) confirmed the influence of the intervention in the large effect size category. In conclusion, lavender aromatherapy was proven to be very effective in reducing insertion pain in hemodialysis patients and is recommended as a complementary therapy.