Elpiani Br Depari
Fakultas Kedokteran Isntitut Kesehatan Medistra Lubuk Pakam

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The Effect of Ultrafiltration Rate Level in Blood Pressure Status Changes in Patients with Chronic Kidney Disease Undergoing Hemodialysis Elpiani Br Depari; Mona Herni Cristina Ritonga; Dewi Cahaya Br Hutabarat; Indria Sisilia Agata; Yoga Wijaya
Medistra Medical Journal (MMJ) Vol 3 No 2 (2026): Medistra Medical Journal (MMJ)
Publisher : Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/m6pdbv92

Abstract

Background: Intradialytic blood pressure changes are common complications in patients undergoing hemodialysis and are suspected to be influenced by the ultrafiltration rate (UFR). These blood pressure fluctuations may affect patient morbidity and mortality through cardiovascular events. Objective: This study aimed to analyze the effect of ultrafiltration rate levels on intradialytic blood pressure status changes based on systolic blood pressure and mean arterial pressure (MAP) parameters. Methods: This study was a prospective observational analytic study conducted among patients with chronic kidney disease (CKD) undergoing hemodialysis at Grandmed Hospital Lubuk Pakam. The UFR was categorized into <10, 10–13, and >13 mL/kg/hour. Blood pressure status changes were classified as stable, hypotensive, and hypertensive. Data were analyzed using the chi-square test with a significance level of p<0.05. Results: A significant association was found between UFR levels and blood pressure status changes based on systolic blood pressure (χ²=12.691; p=0.013), but not on MAP (χ²=7.233; p=0.124). The highest proportion of blood pressure changes was observed in the >13 mL/kg/hour UFR group. Conclusion: Ultrafiltration rate levels significantly influence intradialytic systolic blood pressure changes, higher UFR associated with increased hemodynamic instability.
Erythrocyte Index–Based Morphological Distribution of Anemia in Patients with Chronic Kidney Disease Undergoing Hemodialysis Clarissa Anastasya; Elpiani Br Depari; Bagas Prasetyo; Tabita Syahara
Medistra Medical Journal (MMJ) Vol 3 No 2 (2026): Medistra Medical Journal (MMJ)
Publisher : Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/bnedas20

Abstract

Background: Anemia is a common complication of chronic kidney disease (CKD), mainly caused by erythropoietin deficiency, although factors such as iron deficiency, chronic inflammation, blood loss, and nutritional disorders may also contribute. Erythrocyte indices, including mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC), are useful for evaluating erythrocyte morphology and identifying potential causes of anemia. Objective: To describe the distribution of anemia morphology based on erythrocyte indices in CKD patients undergoing hemodialysis. Methods: This analytical observational study with a cross-sectional design was conducted at the Hemodialysis Unit of Grandmed Hospital, Lubuk Pakam, from January to March 2026. Data were obtained from complete blood count results in patients’ medical records. Hemoglobin, MCV, and MCHC were analyzed, and anemia morphology was classified based on erythrocyte index