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Relationship of acid–base imbalance with hemorrhage volume and mortality in intracerebral stroke hemorrhage Gavin Mukti; Iwan Setiawan; Metana Puspitasari; Sulistyani Sulistyani
JHeS (Journal of Health Studies) Vol. 10 No. 1 (2026): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4008

Abstract

This study aimed to evaluate the relationship between acid-base balance disturbances and intracerebral hemorrhage volume with mortality rates in hemorrhagic stroke cases. The research used an observational analytic design with a cross-sectional approach and was conducted at Dr. Soeratno Gemolong General Hospital, Sragen, from September to November 2024. The study population consisted of medical records of patients diagnosed with hemorrhagic stroke at the hospital between August 2021 and August 2024 who met the inclusion criteria. A total of 50 samples were selected using a purposive sampling technique. Data analysis included univariate analysis, bivariate analysis using the Chi-Square test, and multivariate analysis using logistic regression. The results showed a significant relationship between acid–base balance disturbances and intracerebral hemorrhage volume with mortality in hemorrhagic stroke cases (p=0.001). In addition, intracerebral hemorrhage volume was significantly associated with mortality (p=0.007). Multivariate analysis confirmed that both acid–base imbalance and hemorrhage volume significantly influence mortality outcomes. These findings indicate that acid–base imbalance and intracerebral hemorrhage volume greater than 30 ml are strong predictors of mortality in hemorrhagic stroke patients. Therefore, strict monitoring of arterial blood gases, neurological status, and hemodynamic stability is essential during the acute phase of care. Early detection of physiological deterioration and prompt intervention may help reduce the risk of adverse outcomes. Future research is recommended to use prospective multicenter designs with larger sample sizes to further clarify causal relationships and evaluate whether early correction of acid–base disturbances can improve mortality outcomes in hemorrhagic stroke patients.
Larvicidal Activity of Ethanol Extracts of Bidara (Ziziphus mauritiana) Leaves and Fruits Against Aedes aegypti Rochmadina Suci Bestari; Muhammad Ihsanul Fikri; Riandini Aisyah; Metana Puspitasari; Sri Wahyuni; Mitoriana Porusia
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.586

Abstract

Dengue fever vector control uses abate chemicals can harm the ecosystem. One of the plants that can be used as a natural larvicide is bidara. Bidara leaves and fruits easily available and contains flavonoids, saponins, alkaloids, and tannins. The compound have an impact on the mortality of Aedes aegypti mosquito larvae. Contains study design, subject, methods, data collection and data analysis. Research on ethanol extract of bidara leaves and bidara fruit with Poly Ethylene Glycol (PEG) was experimental laboratory design with post-test only controlled group design. The technique of extraction is maseration. The larvae of Aedes aegypti instar III-IV are used, 800 in total, divided into 8 groups. At 6, 12, 18, and 24 hours, the number of dead larvae was counted .Normality and homegenity tests obtained the results of data not normally distributed and not homogeneous, so it is necessary to do the Kruskall-Wallis non-parametric test followed by Mann-Whitney post hoc .The result is bidara leaf extract with a concentration of 1.5% + 3% PEG resulted in 100% larval death in the 24th hour, meanwhile bidara fruit extract with concentration of 1.5% + 3% PEG resulted 70% larval death in 24th hour. Ethanol extract of bidara leaves has better effectiveness than bidara fruit extract in its ability as a larvicide, where bidara leaf extract with a concentration of 1.5% + 3% PEG resulted in 100% larval death in the 24th hour.
Efektivitas Penyuluhan Kesehatan Sekolah terhadap Peningkatan Pemahaman Anemia pada Remaja Putri: The Effectiveness of School-Based Health Education on Improving Knowledge of Anemia among Adolescent Girls Metana Puspitasari; Nur Mahmudah; Linda Jana Sintaningtyas; Muhammad Daffa Qory; Aura Veranisyah Sudarto
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 11 No. 5 (2026): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v11i5.11791

Abstract

Anemia is a prevalent public health problem among adolescent girls who are undergoing rapid growth and have increased iron requirements. This condition is often worsened by unbalanced dietary habits, restrictive dieting, and limited knowledge about daily nutritional needs and anemia prevention. This community service activity aimed to improve adolescents' understanding of anemia through a school-based health education program. The education was delivered interactively through visual presentations and was accompanied by pre-test and post-test assessments to measure changes in knowledge. A total of 113 students participated in the program. Data were analyzed to evaluate differences in knowledge levels after the intervention. The results showed an increase in the mean knowledge score from 89 to 98, with a statistically significant difference under the Wilcoxon test (p <0,001). Most participants demonstrated improved scores after the session, indicating the effectiveness of the educational method. The program's success was supported by the delivery of communicative materials, the use of easy-to-understand visual media, and strong participant engagement. This activity highlights the important role of health education in improving health literacy among adolescent girls and suggests its potential as a promotive and preventive strategy to reduce anemia. Similar educational programs are recommended for continued implementation to foster long-term anemia-prevention behaviors and support improved health outcomes for future generations.