Article Per Year (5 Year)
p-Index From 2021 - 2026
0.778
P-Index
This Author published in this journals
All Journal Jurnal Analis Farmasi Journal Pharmasci (Journal of Pharmacy and Science) JAF (Jurnal Analis Farmasi) Journal of Pharmaceutical and Sciences.
Fajar Jamaluddin Sandhori
Universitas PGRI Adi Buana Surabaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
UJI KARAKTERISTIK DAN AKTIVITAS ANTIBAKTERI DEODORAN SPRAY EKSTRAK DAUN ANTING-ANTING (Acalypha indica L.) TERHADAP Staphylococcus epidermis Corry' Nanda Nabilla Rahmah; Nadya Ambarwati; Fajar Jamaluddin Sandhori
Jurnal Analis Farmasi Vol 10, No 2 (2025): JURNAL ANALIS FARMASI
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jaf.v10i2.22239

Abstract

Indonesia merupakan negara beriklim tropis dengan suhu tinggi dan kelembapan rendah, yang menyebabkan tubuh mengeluarkan keringat. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi ekstrak daun anting-anting (10%, 20%, 30%) terhadap karakteristik fisik sediaan deodoran spray, meliputi organoleptik, pH, homogenitas, pola semprot, waktu kering, stabilitas, viskositas, uji hedonik, dan aktivitas antibakteri terhadap Staphylococcus epidermidis. Penelitian menggunakan desain eksperimental dengan tiga formula: F1 (10%), F2 (20%), dan F3 (30%). Hasil menunjukkan bahwa seluruh sediaan berbentuk cair dengan warna dan aroma yang bervariasi: F1 berwarna coklat muda beraroma lavender, F2 coklat beraroma lavender, dan F3 coklat tua dengan aroma khas anting-anting. Semua formula memiliki pH 5, sesuai standar, dan terdapat perbedaan signifikan (p = 0.010). Sediaan homogen, tanpa partikel kasar atau endapan. Pola semprot rata-rata 6 cm, waktu kering 47 detik, dan stabilitas baik. Viskositas memenuhi kriteria (56,30 ± 1,51 cps; p = 0.015). Uji hedonik menunjukkan formula F2 paling disukai oleh 30 responden berdasarkan aroma, warna, dan tekstur. Sementara itu, F3 (30%) menunjukkan aktivitas antibakteri yang paling kuat terhadap S. epidermidis.
UJI KARAKTERISTIK DAN AKTIVITAS ANTIBAKTERI DEODORAN SPRAY EKSTRAK DAUN ANTING-ANTING (Acalypha indica L.) TERHADAP Staphylococcus epidermis Corry' Nanda Nabilla Rahmah; Nadya Ambarwati; Fajar Jamaluddin Sandhori
Jurnal Analis Farmasi Vol 10, No 2 (2025): JURNAL ANALIS FARMASI
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jaf.v10i2.22239

Abstract

Indonesia merupakan negara beriklim tropis dengan suhu tinggi dan kelembapan rendah, yang menyebabkan tubuh mengeluarkan keringat. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi ekstrak daun anting-anting (10%, 20%, 30%) terhadap karakteristik fisik sediaan deodoran spray, meliputi organoleptik, pH, homogenitas, pola semprot, waktu kering, stabilitas, viskositas, uji hedonik, dan aktivitas antibakteri terhadap Staphylococcus epidermidis. Penelitian menggunakan desain eksperimental dengan tiga formula: F1 (10%), F2 (20%), dan F3 (30%). Hasil menunjukkan bahwa seluruh sediaan berbentuk cair dengan warna dan aroma yang bervariasi: F1 berwarna coklat muda beraroma lavender, F2 coklat beraroma lavender, dan F3 coklat tua dengan aroma khas anting-anting. Semua formula memiliki pH 5, sesuai standar, dan terdapat perbedaan signifikan (p = 0.010). Sediaan homogen, tanpa partikel kasar atau endapan. Pola semprot rata-rata 6 cm, waktu kering 47 detik, dan stabilitas baik. Viskositas memenuhi kriteria (56,30 ± 1,51 cps; p = 0.015). Uji hedonik menunjukkan formula F2 paling disukai oleh 30 responden berdasarkan aroma, warna, dan tekstur. Sementara itu, F3 (30%) menunjukkan aktivitas antibakteri yang paling kuat terhadap S. epidermidis.
Formulasi dan Uji Karakterisasi Fisikokimia Gel Ekstrak Ranting Patah Tulang (Euphorbia tirucalli) Nadya Ambarwati; Fajar Jamaluddin Sandhori; Annah Hubaedah
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1525

Abstract

Euphorbia tirucalli L. twigs contain various secondary metabolites, including alkaloids, flavonoids, tannins, saponins, and steroids, which have potential antibacterial activity. This study aimed to evaluate the effect of different concentrations of Euphorbia tirucalli twig extract on the physicochemical characteristics of gel formulations. Three gel formulations containing 15% (F1), 20% (F2), and 25% (F3) extract were prepared and evaluated for organoleptic properties, pH, spreadability, adhesiveness, homogeneity, and irritation potential. Quantitative data were analyzed using One-Way ANOVA at a 95% confidence level (α = 0.05). The results showed that all formulations produced homogeneous, semi-solid gels with a soft texture and did not cause skin irritation. The pH values ranged from 5.14 ± 0.193 to 5.67 ± 0.011, which were within the physiological skin pH range. The spreadability values ranged from 5.08 ± 0.310 to 5.19 ± 0.209 cm, meeting the acceptable criteria for topical gel preparations. All formulations exhibited good adhesiveness, with adhesion times exceeding 4 seconds (4.45 ± 1.673 to 4.46 ± 1.075 seconds). Statistical analysis indicated that variations in extract concentration had no significant effect on pH, spreadability, adhesiveness, homogeneity, or irritation parameters, with all p-values greater than 0.05. However, increasing extract concentration resulted in a visually darker gel color. In conclusion, all gel formulations fulfilled the physicochemical requirements for topical preparations, and extract concentrations ranging from 15% to 25% did not significantly affect the physicochemical characteristics of the gel, indicating their potential for further development as a natural topical dosage form.
Formulation and Characterisation of Liquid Bath Soap Containing Rosella Flower Extract (Hibiscus sabdariffa L.): Formulasi dan Uji Karakteristik Sabun Mandi Cair Ekstrak Bunga Rosella (Hibiscus sabdariffa L.) Silvi Agustin; Nadya Ambarwati; Fajar Jamaluddin Sandhori
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 11 No. 2 (2026): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v11i2.566

Abstract

The skin is the body's primary protective organ against pathogenic microorganisms, so maintaining skin cleanliness is very important. Liquid soap is becoming an increasingly popular choice because it is practical and hygienic. Product innovation in soap formulation by adding natural ingredients such as rosella flower extract (Hibiscus sabdariffa L.), which contains flavonoids, anthocyanins, and saponins,has the potential to provide antioxidant and antibacterial benefits. This study aims to investigate the effect of varying concentrations of rosella flower extract (0%, 1%, 3%, and 5%) on the physical characteristics of liquid soap, including organoleptic testing, pH, viscosity, homogeneity, foam height, and hedonic testing. The extract was obtained using the percolation method with 70% ethanol as the solvent. The results showed that the liquid soap containing rosella flower extract met all evaluation criteria for the formulation. The hedonic test conducted by 30 respondents indicated that the formulation with 1% extract (F1) was the most preferred based on color, aroma, and texture. In conclusion, osella flower extract can be used as liquid soap with physical characteristics that meet the requirements in pH testing (6.36–6.90), viscosity (645.0–771.6 cPs), foam height (30.3–42.5 mm), and homogeneity (homogeneous). Statistical tests showed significant differences (p < 0.05) in the test parameters (pH, viscosity, and foam height). Meanwhile, Formulation 1 is the best formulation with the highest scores in color and texture parameters in the hedonic test.
Co-Authors Corry&#039; Nanda Nabilla Rahmah Hubaedah, Annah Nadya Ambarwati Silvi Agustin