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Tika Afriani
Universitas Mohammad Natsir Bukittinggi, Indonesia
Medicine & Pharmacology

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Korelasi Kepatuhan Pasien dalam Pengobatan Tuberkulosis Paru di Puskesmas Pakan Kamis, Kecamatan Tilatang Kamang Kabupaten Agam Nursyamsi Nursyamsi; Rahman S. Sianu; Tika Afriani
Journal of Science and Clinical Pharmacy Research Vol. 2 No. 1 (2026): February 2026
Publisher : LPPM Universitas Mohammad Natsir Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1144/jscpr.v2i1.400

Abstract

Tuberkulosis paru adalah penyakit yang sangat menular yang disebabkan oleh Mycobacterium Tuberkulosisyang menyerang paru-paru. Indonesia sendiri termasuk dalam lima negara dengan kasus Tuberkulosis tertinggi. Salah satu faktor kunci yang mempengaruhi keberhasilan pengobatan tuberkulosis paru adalah kepatuhan pasien dalam mengkonsumsi obat. Tujuan dari penelitian adalah untuk menggambarkan sejauh mana korelasi kepatuhan terhadap pengobatan tuberkulosis di Puskesmas Pakan Kamis serta untuk mengidentifikasi faktor-faktor yang mempengaruhi penderita Tuberkulosis Paru untuk menghentikan pengobatan sebelum selesai di Puskesmas Pakan Kamis. Penelitian ini menggunakan pendekatan mixed method yaitu menggabungkan metode kuantitatif dan kualitatif dalam satu rangkaian studi. Teknik pengambilan sampel adalah total sampling dengan jumlah sampel sebanyak 16 responden. Hasil uji analisis korelasi menunjukan nilai p-value < 0,05, maka disimpulkan terdapat korelasi antara kepatuhan terhadap beberapa faktor antara lain umur, tingkat pendidikan, lama menderita Tuberkulosis, pengetahuan pasien tentang Tuberkulosis, motivasi pasien, efek samping obat.di Puskesmas Pakan Kamis. Sebaliknya tidak terdapat korelasi antar kepatuhan dengan aksebilitas fasilitas kesehatan, kepatuhan dengan jenis kelamin, kepatuhan dengan kualitas layanan kesehatan. Bagi tenaga kesehatan di puskesmas, disarankan untuk memberikan edukasi secara berkelanjutan dan interaktif kepada pasien tentang penyakit Tuberkulosis, pentingnya pengobatan yang tuntas, dan dampak jika pengobatan dihentikan
PENGARUH PENGGUNAAN OBAT GOLONGAN CALSIUM CHANNEL BLOCKERS (CCB) DIBANDINGKAN ANGIOTENSIN RECEPTOR BLOCKERS (ARB) TERHADAP LUARAN KLINIS PASIEN HIPERTENSI DENGAN GANGGUAN GINJAL DI RSI IBNU SINA BUKITTINGGI Annisa Rahim; Tika Afriani; Ariesta Kirana Efmisa
Journal of Science and Clinical Pharmacy Research Vol. 2 No. 1 (2026): February 2026
Publisher : LPPM Universitas Mohammad Natsir Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1144/jscpr.v2i1.401

Abstract

Hypertension is a major risk factor for chronic kidney disease (CKD) with a complex bidirectional relationship. Appropriate selection of antihypertensive drugs in patients with hypertension and end-stage CKD is crucial to prevent disease progression and improve clinical outcomes. This study aimed to compare the effectiveness of Calcium Channel Blockers (CCB) and Angiotensin Receptor Blockers (ARB) on changes in blood pressure and kidney function in patients with hypertension and stage 5 CKD at RSI Ibnu Sina Bukittinggi. A descriptive-analytic design with a retrospective approach was employed, involving 30 patients who met the inclusion criteria from a total of 78 patients during the period February 2023–December 2024. Parameters observed included systolic/diastolic blood pressure, serum creatinine, glomerular filtration rate (GFR), and urea levels before and after therapy. The results showed that both therapy groups experienced reductions in blood pressure and improvements in kidney function. The decrease in systolic/diastolic blood pressure for CCB was 14.7/11.4 mmHg, while for ARB it was 14.2/11.2 mmHg. Increases in GFR, reductions in creatinine, and decreases in urea occurred in both groups with no statistically significant differences (p>0.05). In conclusion, CCB and ARB have comparable clinical effectiveness in controlling blood pressure and improving kidney function parameters in patients with hypertension and end-stage CKD.
ANALISIS HUBUNGAN LITERASI KESEHATAN TERHADAP PERILAKU PENGELOLAAN OBAT SISA PADA MASYARAKAT KOTA BUKITTINGGI Suzy Andriyani Sucipto Harjo; Khairil Armal; Tika Afriani
Journal of Science and Clinical Pharmacy Research Vol. 2 No. 1 (2026): February 2026
Publisher : LPPM Universitas Mohammad Natsir Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1144/jscpr.v2i1.430

Abstract

Health literacy is an important aspect in making health-related decisions, including behaviors in managing leftover medicines. Improper storage and disposal of unused or expired medicines can lead to serious issues such as drug misuse and environmental pollution. This study aimed to determine the relationship between the level of health literacy and leftover medicine management behavior among the community of Bukittinggi City. This research employed an observational analytic method with a cross-sectional design and cluster sampling technique involving 100 respondents. Data were collected using the HLS-EU-SQ10-IDN questionnaire to measure health literacy, along with an additional questionnaire to assess knowledge and behavior regarding leftover medicine management. The results showed that most respondents had a moderate level of health literacy (33.12%), good knowledge (96%), and good management behavior (76%). However, there was no significant relationship between health literacy level and knowledge (p = 0.613) or between health literacy and management behavior (p = 0.253). In conclusion, improving health literacy alone is insufficient to change community behavior in managing leftover medicines. Therefore, specific educational approaches, adequate disposal facilities, and clear household-level pharmaceutical waste regulations are needed to prevent potential health and environmental risks.
Co-Authors Annisa Rahim Ariesta Kirana Efmisa Khairil Armal Nursyamsi Nursyamsi Rahman S. Sianu Suzy Andriyani Sucipto Harjo