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All Journal Diagnosis: Jurnal Ilmiah Kesehatan Tropis: Jurnal Riset Teknologi Laboratorium Medis
Rezjita Asti Pratiwi
Universitas Palangka Raya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Literature Study of Soil Transmitted Helminths (STH) Infections in Children: Laboratory Examination and Mortality Risk Agnes Cecilia; Ahmad Abid Syarif; Arya Jagad Mulawarwan; Herciella Bernadetha; Joice Earlene Nathaniella Taffy; Rezjita Asti Pratiwi
Tropis: Jurnal Riset Teknologi Laboratorium Medis Vol 3 No 1 (2026): Tropis: Jurnal Riset Teknologi Laboratorium Medis
Publisher : Program Studi Teknologi Laboratorium Medis

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Abstract

Soil-Transmitted Helminth (STH) infections represent a global health problem, imposing a substantial burdenon children due to poor sanitation. This literature review aims to analyze laboratory examinations in STH infectionsamong children and their association with mortality risk. The study employed a Systematic Literature Review methodthrough searches in PubMed, ScienceDirect, and Google Scholar using relevant keywords, restricted to publications fromthe past ten years. The findings indicate that Ascaris lumbricoides frequently causes acute complications such asmechanical asphyxia and intestinal obstruction, which may lead to death if not promptly managed. Trichuris trichiurainfection can result in chronic complications including dysentery syndrome, severe anemia, stunting, and malnutrition,all of which increase the risk of mortality in children. Meanwhile, hookworm infection may lead to severe anemia andhypoalbuminemia in children. Laboratory examinations such as stool microscopy, histopathology, radiology, andultrasonography are essential for establishing diagnosis, assessing disease severity, and guiding therapy. In conclusion,early detection of STH infections through laboratory investigations plays a critical role in preventing seriouscomplications and reducing mortality risk in children, underscoring the need for strategies that extend beyond dewormingprograms to include nutritional improvement and the management of comorbid conditions.
Peran ATLM Dalam Pengembangan Dan Pelaksanaan Teknik Diagnostik Helicobacter Pylori : Tinjauan Literatur Terhadap Pemeriksaan Mikrobiologi Dan Molekuler Angga Pratama Putra; Agnes Cecilia; Stepany Teguh; Hanasia Hanasia; Rezjita Asti Pratiwi; Kezia Dona Gracia; Yuwita Laudya Christy; Gilbert Pahlawan Jonathan Gultom
Diagnosis Jurnal Ilmiah Kesehatan Vol. 21 No. 1 (2026): Diagnosis: Jurnal Ilmiah Kesehatan
Publisher : STIKES Nani Hasanuddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35892/djik.v21i1.3038

Abstract

Helicobacter Pylori (H. pylori) adalah bakteri gram negatif berflagel yang ditemukan di saluran pencernaan dapat menyebabkan komplikasi serius bila tidak ditangani dengan cepat dan tepat. Deteksi H. pylori dilakukan di laboratorium dengan pemeriksaan gold standar yaitu kultur dimana pemeriksaan dilakukan oleh seorang Ahli Teknologi Laboratorium Medis (ATLM). Penelitian ini dilakukan dengan pendekatan Systematic literature review dari 205 literatur dengan 17 literatur yang memenuhi kriteria inklusi mengenai berbagai metode diagnostik H. pylori, baik invasif maupun non-invasif. Tinjauan ini juga menyoroti peran penting seorang ATLM dalam seluruh tahapan pemeriksaan, mulai dari pengelolaan sampel, hingga validasi hasil. Terdapat beberapa spesimen untuk dilakukan pemeriksaan H. pylori yaitu biopsi lambung, feses, saliva, jaringan lambung, dan biopsi paru. Teknik diagnostik H. pylori mencangkup Urea Breath Test (UBT), Stool Antigen Test (SAT), rt-PCR (real-time PCR), ELISA, Rapid Urease Test (RUT), histologi, dan kultur. Biomarker untuk diagnosis dan terapi infeksi H. pylori yaitu Protein HpaA, gen VacA dan gen CagA.
Co-Authors Agnes Cecilia Ahmad Abid Syarif Angga Pratama Putra Arya Jagad Mulawarwan Gilbert Pahlawan Jonathan Gultom Hanasia Hanasia Herciella Bernadetha Joice Earlene Nathaniella Taffy Kezia Dona Gracia Stepany Teguh Yuwita Laudya Christy