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Perubahan Tekanan Intraokular Sebelum dan Sesudah Operasi Katarak Dengan Teknik Fakoemulsifikasi Pada Pasien Katarak Senilis di Rumah Sakit Mata Medan Baru Muhammad Baihaqi; Aryani Atiyatul Amra; Muhammad Rusda; Putri Chairani Eyanoer
Jurnal Impresi Indonesia Vol. 4 No. 11 (2025): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i11.7172

Abstract

Katarak merupakan penyebab kebutaan yang paling utama di dunia, estimasi WHO pada tahun 2019, 65,2 juta orang mengalami gangguan penglihatan akibat katarak. Teknik pembedahan katarak yang sering digunakan saat ini adalah fakoemulsifikasi. Tekanan intraokular merupakan salah satu parameter pemantauan dalam keberhasilan operasi katarak. Penelitian ini bertujuan untuk melihat perubahan tekanan intraokular sebelum dan sesudah operasi katarak pasca fakoemulsifikasi di Rumah Sakit Mata Medan Baru. Metode penelitian berupa pasien katarak senilis berusia > 40 tahun yang dilakukan tindakan fakoemulsifikasi dari bulan Agustus sampai Oktober 2024 diinklusikan dalam penelitian case-series ini. Sebanyak 440 orang sampel diambil dengan teknik konsekutif sampling. Tekanan intraokular diukur dengan besaran nilai mm Hg. Dilakukan pengukuran tekanan intraokular 1 jam sebelum operasi, hari ke-1, hari ke-7 dan hari ke-14 pasca operasi. Hasil menunjukan analisis dengan uji T-test berpasangan didapatkan perubahan yang signifikan antara nilai tekanan intraokular sebelum operasi dengan hari ke-1 pasca operasi (p=0.00), hari ke-7 pasca operasi (p=0.00) dan hari ke-14 pasca operasi (p=0.00). Terdapat perubahan tekanan intraokular sebelum dan sesudah operasi katarak pasca fakoemulsifikasi di Rumah Sakit Mata Medan Baru.
Characteristics of Genetic Susceptibility in Lung Cancer Patients in North Sumatra Population, Indonesia Putri Aulia Anwar; Noni Novisari Soeroso; Setia Putra Tarigan; Putri Chairani Eyanoer
Indonesian Health Journal Vol. 5 No. 2 (2026): Indonesian Health Journal
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/ihj.v5i2.883

Abstract

Lung cancer remains a major global health problem and the leading cause of cancer-related mortality worldwide. Although smoking and environmental exposure are the dominant risk factors, genetic susceptibility and family history may also contribute to lung cancer development, particularly among individuals with inherited cancer predisposition. This study aimed to describe the characteristics of genetic susceptibility among lung cancer patients in the North Sumatra population, Indonesia, with emphasis on family history of lung cancer and other cancers. A descriptive observational design was employed, conducted from August to November 2024 at Adam Malik Hospital, Universitas Sumatera Utara Hospital, and Santa Elisabeth Hospital. A total of 240 patients with histopathologically confirmed small-cell lung cancer and non-small-cell lung cancer were included through consecutive sampling. Data were collected from medical records, including sociodemographic characteristics, clinical information, and family cancer history, and were analyzed descriptively using IBM SPSS version 26. The results showed that patients had a mean age of 59.12 ± 13.22 years, were predominantly male, and were mostly of Batak ethnicity. Regarding familial susceptibility, 5.4% had a family history of lung cancer, 34.2% had a family history of other cancers, and 60.4% had no family history of cancer. These findings indicate that family history should be considered in lung cancer risk assessment. Integrating familial cancer evaluation into routine clinical practice may support early screening, prevention, and personalized intervention strategies.
Characteristics of Tumor Marker on Mediastinal Tumors Novpiodita Pratiwi; Setia Putra Tarigan; Novi Novisari Soeroso; Putri Chairani Eyanoer
Indonesian Health Journal Vol. 5 No. 2 (2026): Indonesian Health Journal
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/ihj.v5i2.888

Abstract

Mediastinal tumors are rare thoracic malignancies that pose diagnostic and therapeutic challenges due to their anatomical proximity to vital organs and diverse histopathological features. Early detection and accurate characterization are essential for effective management. This study aimed to describe the characteristics of tumor markers and their diagnostic relevance in patients with mediastinal tumors treated at Adam Malik General Hospital, Medan, Indonesia. A descriptive observational study using a case series design was conducted on 43 patients diagnosed with histopathologically confirmed mediastinal tumors from 2020 to 2024. Data on demographics, tumor histopathology, tumor location, and tumor marker levels (LDH, AFP, B-HCG, and CEA) were collected from medical records. Statistical analysis was performed using SPSS 26.0, with categorical variables expressed as frequencies and percentages, and numerical variables as mean ± standard deviation. The results indicated that the majority of patients were male (76.7%), with a mean age of 40.7 ± 15.5 years. Lymphoma (39.5%) and thymoma (37.2%) were the most common tumor types, predominantly located in the anterior mediastinum (76.7%). LDH was elevated in 76.7% of cases, particularly in germ cell tumors and lymphomas, while AFP and B-HCG elevations were mainly observed in germ cell tumors. CEA had limited diagnostic utility. The study concludes that integrating clinical, histopathological, and tumor marker data enhances diagnostic accuracy, and that LDH, AFP, and B-HCG serve as valuable supportive biomarkers for mediastinal tumor evaluation.