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All Journal Ekonomi Bisnis Spizaetus: Jurnal Biologi dan Pendidikan Biologi Proceeding Biology Education Conference
Neila Putri Shofiyana
Universitas Islam Negeri Sayyid Ali Rahmatullah Tulungagung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Inverse Docking dan Identifikasi Protein Target Metabolik Sekunder Senna siamea terhadap Propionibacterium acnes Neila Putri Shofiyana; Achmad Nurul Yaqin
Proceeding Biology Education Conference: Biology, Science, Enviromental, and Learning Vol 20, No 1 (2023): Proceeding Biology Education Conference
Publisher : Universitas Sebelas Maret

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Abstract

Tanaman johar (Senna siamea) diketahui memiliki aktivitas antibakteri dan telah banyak dimanfaatkan sebagai obat tradisional khususnya daunnya. Aktivitas antibakteri ekstrak daun johar telah banyak dilaporkan mampu menghambat pertumbuhan baik bakteri Gram positif dan Gram negatif. Dibandingkan bakteri lain, Konsentrasi Hambat Minimum (MIC) ekstrak daun johar terhadap Propionibacterium acnes dilaporkan jauh lebih rendah. Namun, mekanisme antibakteri dan protein reseptor targetnya belum diketahui. Penelitian ini bertujuan untuk menentukan protein target utama dan senyawa aktif dalam S. siamea untuk memahami mekanisme antibakterinya. Metode yang digunakan adalah molekuler docking senyawa yang dilaporkan pada ekstrak S. siamea pada beberapa protein bakteri P. acnes menggunakan Swissdock. Hasil dengan konformasi paling stabil dianalisis lebih lanjut dengan metode Density Functional Theory (DFT) menggunakan Gaussian 09 pada level teori HF/3-21G dan semiempirik PM6 dilanjutkan dengan analisis Interaksi Non-Kovalen (NCI) menggunakan Multiwfn. Kesimpulan dari penelitian ini adalah lipase pembentuk biofilm adalah protein target dari senyawa polar dalam daun S. siamea terutama siamosida A.
Penguatan Karakter Hidup Sehat melalui Permainan Konvensional sebagai Fondasi Menyongsong Generasi Emas 2045 Nanang Purwanto; M Iqbal Maulana; Neila Putri Shofiyana; Imel Wijayanti; Nadila Erdina Putry
Spizaetus: Jurnal Biologi dan Pendidikan Biologi Vol 6 No 3 (2025): Spizaetus: Jurnal Biologi dan Pendidikan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55241/spibio.v6i3.634

Abstract

Conventional games are a national cultural heritage, now gradually fading and rarely found in society. This is due to the development of science and technology. This phenomenon was found among students at SDN 2 Jajar, Trenggalek Regency. Online games involve the sense of sight which is at risk of bad for children's motor and social development, while conventional games involve body parts to move, so that the body is healthier, stronger, and fitter. The population in the study included all children aged 6 to 12 years in Jajar Village. The sample included 31 students from grades one to six and 31 parents of SDN 2 Jajar students. Data collection techniques were through observation, interviews, and documentation. Data analysis techniques were descriptive qualitative. This paper explains efforts to arouse the enthusiasm and love of students at SDN 2 Jajar and Madrasah Ibtidaiyah Jajar for conventional games that are the foundation of a healthy lifestyle. The socialization was held on January 3-4, 2024, while practical activities were held on January 7 and 21, 2024. Conventional games that were socialized included Rangku Alu, Egrang, Bakiak, Gobak Sodor. The results of the socialization showed a positive response from students and parents/guardians of SDN 2 Jajar. The aim of this activity is to realize healthy children's characters to welcome the golden generation of 2045.
MSME Business Facilitation through QRIS, Google Maps, and Product Catalogues: A Maqashid Syariah Perspective Neila Putri Shofiyana; Ariful Helmi Junaidi; Lukman Hakim; Laita Kasififi Duriyatul Suryani; Rizqi Fajar Rahmawati
Jurnal Ilmiah Ekonomi Bisnis Vol. 31 No. 2 (2026)
Publisher : Universitas Gunadarma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35760/eb.2026.v31i2.882

Abstract

Digital business facilitation is increasingly relevant for micro, small, and medium enterprises (MSMEs) seeking better transaction practices, business visibility, and product information access. This study examines documented implementation of QRIS, Google Maps, and a product catalogue among businesses in Ngepel Hamlet, Sempu Village, Ponorogo Regency, and interprets these outputs through a maqashid syariah perspective. Using a qualitative document-based case study supported by a literature review, it analyses the unpublished internal activity report of the Kelompok 3 Persemakmuran KPM community-service program (July–August 2026), with academic literature on MSME digitalization and maqashid syariah as the interpretive foundation. The documented outputs comprise four QRIS adoptions, ten Google Maps registrations (nine MSMEs and one village-owned enterprise/BUMDes), and two printed catalogue booklets covering seven MSMEs. The analysis suggests that QRIS supports hifz al-mal through traceable, lower-risk transactions and taysir through transactional convenience, while Google Maps and product catalogues support ‘adl by improving accessibility and clarity of business information and potentially reducing gharar. These findings concern documented outputs and their theoretical implications, not measured changes in sales, transaction volume, consumer trust, or economic empowerment. The Ngepel case illustrates how complementary facilitation tools may align with maqashid syariah, underscoring the need for longitudinal research on economic outcomes.
Co-Authors Achmad Nurul Yaqin Ariful Helmi Junaidi Imel Wijayanti Laita Kasififi Duriyatul Suryani Lukman Hakim M Iqbal Maulana Nadila Erdina Putry Nanang Purwanto Rizqi Fajar Rahmawati