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All Journal JOPS (Journal Of Pharmacy and Science)
Raja Adli Husein
Jurusan Kimia, FMIPA , Universitas Riau
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Uji Aktivitas Antibakteri Ekstrak Etil Asetat Jamur Gliocladium sp T.N.C73 dengan Kromatografi Lapis Tipis-Bioautografi Emma - Susanti; Rahayu Utami; Raja Adli Husein; Titania T Nugroho
JURNAL FARMASI DAN MAKANAN Vol 9 No 2 (2026): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i2.7566

Abstract

Gliocladium sp. is a fungus that functions as a biological control agent against plant pathogens. Research on the activity of Gliocladium sp. not yet against human pathogens. The aim of this study was to determine the antibacterial profile of ethyl acetate extracts of Gliocladium sp. T.N.C73 (LBKURCC3) using the TLC-bioautography method against E. coli ATCC 25922 and S. aureus ATCC 25923. The test results showed that the ethyl acetate extract of the fungus Gliocladium sp. exhibited antibacterial activity against S. aureus dan tidak menghambat E. coli whereas against, it showed antibacterial activity characterised by the formation of a clear area and verified with resazurin (blackish blue colour). Resazurin is used as a redox indicator in bacterial cell viability and proliferation tests. The conclusion of this study is that the ethyl acetate extract of Gliocladium sp. T.N.C73 (LBKURCC3) fungus can inhibit S. aureus bacteria.
Co-Authors Rahayu Utami Ronapadua Musyirna Rahmah Nasution Sahara dan Emma Susanti Titania T Nugroho