Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Kurniati, Amiroh
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Mid Regional Pro-Adrenomedullin, Lactate, and Risk Factors as Predictors of Sepsis Severity Andi Widagdo, Heribertus; Kurniati, Amiroh; Pramudianti, Maria Immakulata Diah
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 3 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i3.2352

Abstract

Sepsis is a syndrome determined by pathogenic and host factors, including gender, age, comorbidities, and bacteremia. A high level of MR pro-ADM is associated with vascular relaxation, while a high lactate level indicates tissue hypoxia and anaerobic metabolism. This study aimed to assess MR pro-ADM and lactate as predictors of sepsis severity by considering age, gender, comorbidities, clinical screening, and bacterial culture result factors. This study used an observational analytic research design with a prospective cohort approach. Researchers consecutively collected a sample of 80 sepsis patients at Dr. Moewardi Regional General Hospital (RSDM) in February-March 2023. Clinical characteristics, demographics, physical examinations, and laboratory results were collected from medical records and the Hospital Information System (HIS) of RSDM. MR pro-ADM and lactate levels were measured by Enzyme-Linked Immunosorbent Assay (ELISA) and enzymatic amperometric methods. There were significant differences in severity and mortality predictor variables (clinical screening, log_lactate >0.40, bacterial culture). The ranking of the strength of association of predictors of severity was clinical screening ((Odds Ratio (OR)=15.40), bacterial culture results (OR=3.7), log_lactate (OR=2.74). Clinical screening, lactate, and culture results were independent predictors of sepsis severity. Multi-center studies with more complete data, considering other factors that influence sepsis, and using more accurate methods of measuring ADM and lactate are recommended.
Agreement between SARS-CoV-2 Antibody Test Results Using FIA and ECLIA Methods in Post-COVID-19 Infection and Sinovac Vaccination Hubertus, Johanis; Sidharta, Brigitte Rina Aninda; Kurniati, Amiroh
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 32 No. 1 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v32i1.2419

Abstract

Coronavirus Disease 2019 (COVID-19) is a pandemic that needs to be urgently addressed through the formation of antibodies, such as vaccination.  Automated SARS-CoV-2 antibody tests in hospitals are limited due to maintenance issues and high costs.  This study aimed to determine the agreement of SARS-CoV-2 antibody test results using the FIA and ECLIA methods in post-COVID-19 infection and Sinovac vaccination. An observational analytical study with a cross-sectional approach was conducted at Dr.  Moewardi Hospital from September to November 2022. The FIA method (FRENDTM NanoEntek) and ECLIA method (Cobas e411) were employed, revealing significant differences and strong correlations in both the COVID-19 infection group (r=0.9999, p<0.0001) and the Sinovac vaccination group (r=0.997, p<0.0001).  The Passing and Bablok test showed systematic, proportional, and random differences in both the COVID-19 infection group (95% CI = -65.60 to -41.97; 95% CI = 3.42 to 3.70; 95% CI = -4.76 to 4.76) and the Sinovac vaccination group (95% CI = -21.71 to -8.69; 95% CI = 2.23 to 2.96;  95% CI = -12.37 to 12.37). In conclusion, there is no method of agreement between the results of SARS-CoV-2 antibody testing using the FIA and ECLIA methods in both post-COVID-19 infection and post-Sinovac vaccination groups
Co-Authors Andi Widagdo, Heribertus Hubertus, Johanis Pramudianti, Maria Immakulata Diah Sidharta, Brigitte Rina Aninda