Yenny Sulisma
Universitas Malikussaleh

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Gambaran Kualitas Hidup pada Pasien Penderita Diabetes Melitus Tipe 2 di RSUD Cut Meutia Aceh Utara Hilda Amalia; Yenny Sulisma
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 2 (2026): Maret: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i2.2213

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion, insulin action, or both. Globally, DM continues to pose a growing health challenge, particularly type 2 DM, which is closely associated with insulin resistance. In this condition, body cells fail to respond effectively to insulin, so even though the pancreas initially produces sufficient or excessive amounts of insulin, its effectiveness gradually declines. Over time, pancreatic beta-cell function deteriorates, further exacerbating chronic hyperglycemia. This persistent condition may lead to long-term complications, including nephropathy, retinopathy, neuropathy, and cardiovascular diseases, through mechanisms such as oxidative stress, inflammation, and the formation of advanced glycation end products (AGEs). The prevalence of type 2 DM is expected to continue rising, including in Indonesia, highlighting the need for comprehensive management strategies. An important aspect of DM management is the assessment of health-related quality of life. Quality of life reflects an individual’s perception of their health status within social and cultural contexts. This can be evaluated using generic instruments such as the WHOQOL-BREF questionnaire. In this case report, the quality of life of a patient with type 2 DM was assessed using the WHOQOL-BREF to provide a comprehensive understanding of the disease’s impact on the patient’s daily life.
Studi Kasus Hipertiroid pada Laki-laki Usia 41 Tahun Afifah Mardhatillah; Yenny Sulisma
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 3 No. 3 (2025): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v3i3.5304

Abstract

Hyperthyroidism is a condition characterized by elevated levels of circulating thyroid hormones due to hyperactivity of the thyroid gland, commonly caused by Graves’ disease, toxic multinodular goiter, or toxic adenoma. It is marked by increased levels of free thyroxine (fT4), thyroxine (T4), free triiodothyronine (fT3), or triiodothyronine (T3), along with suppressed levels of thyroid-stimulating hormone (TSH). In this case study, a 41-year-old male presented with an enlarging neck mass and was diagnosed with hyperthyroidism, having been on antithyroid medication for the past three months. The patient also reported palpitations, hand tremors, excessive sweating, and a 15 kg weight loss over the past three years. Based on medical history, physical examination, supporting investigations, and prior diagnosis, the patient was confirmed to have hyperthyroidism. He received appropriate treatment and was discharged after clinical improvement.