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All Journal Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal 'Aisyiyah Medika Jurnal Kesehatan Farmasi
Ramadhiani, Aninditha Rachmah
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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Mini Review Pharmacy Oncology: Current Trends and Future Directions Mangunsong, Sonlimar; Ramadhiani, Aninditha Rachmah; Astuti, Vera
Jurnal Kesehatan Farmasi Vol 7 No 1 (2025): Jurnal Kesehatan Farmasi
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkpharm.v7i1.2714

Abstract

Abstract Pharmacy Oncology has made significant strides in improving cancer care through the development of targeted therapies, immunotherapies, pharmacogenomics, and nanotechnology. However, challenges remain in optimizing drug efficacy, managing adverse events, and ensuring equitable access to these advanced treatments. The evolving role of pharmacists in oncology will be crucial in addressing these challenges, ensuring that patients benefit from the latest advancements in cancer care. Pharmacy oncology plays a critical role in advancing cancer treatment by improving the efficacy, safety, and accessibility of therapies. This review highlights current trends in pharmacy oncology, including the emergence of targeted molecular therapies, immunotherapy innovations, nanoparticle-based drug delivery, and the integration of personalized medicine. Key challenges such as high treatment costs, drug resistance, and access disparities are explored alongside their implications for patient care. Future opportunities are identified, emphasizing advancements in pharmacogenomics, digital health technologies, and collaborative approaches to address unmet needs. This review underscores the necessity for continuous innovation to enhance therapeutic outcomes and improve the quality of life for cancer patients. Keywords: Oncology Pharmacy ; targeted therapies, immunotherapy, pharmacogenomics, Review
EVALUASI KETERSEDIAAN PELAYANAN INFORMASI OBAT RESEP ISONIAZID Delina, Susanti; Ramadhiani, Aninditha Rachmah; Rosita, Meri; Ruliyani, Iqlima
Jurnal 'Aisyiyah Medika Vol 8, No 2: Agustus 2023 Jurnal 'Aisyiyah Medika
Publisher : stikes 'aisyiyah palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36729/jam.v8i2.1087

Abstract

ABSTRAKLatar Belakang: Pemerintah mengeluarkan Peraturan Menteri Kesehatan RI No. 73 tahun 2016 tentang Standar Pelayanan Kefarmasian di Apotek dengan tujuan utama adalah untuk melindungi masyarakat dari pelayanan yang tidak profesional. Seluruh tenaga kefarmasian dalam melaksanakan tugas profesinya harus mengacu pada standar ini. Tujuan: Menggambarkan profil pelayanan resep obat isoniazid meliputi ketersediaan pelayanan informasi obat yang diberikan oleh staf farmasi di apotek. Metode: Jenis penelitian ini adalah non-eksperimental dengan rancangan penelitian bersifat deskriptif melalui pengamatan secara observasi partisipatif partil. Populasi target pada penelitian ini adalah seluruh apotek di Kota Palembang. Sampel terdiri dari 76 apotek yang telah ditentukan dengan menggunakan metode cluster random sampling. Hasil: Dari 76 apotek sampel, terdapat hanya 11 apotek yang tidak memberikan pelayanan informasi obat. 65 apotek (86%) hanya memberikan informasi cara pemakaian saja. Sebanyak 4 apotek (5,2%), sebanyak 51 apotek (67,10%) memberikan informasi manfaat obat, sebanyak 29 apotek   (38,15%) yang memberikan informasi efek samping dari obat tersebut sebanyak 8 apotek (10,52%) yang memberikan informasi jangka waktu pengobatan. Saran: Perlu adanya pelatihan atau pendidikan berkelanjutan untuk meningkatkan kemampuan apoteker dalam melakukan pelayanan kesehatan khususnya dalam pelayanan informasi obat menurut Standar Pelayanan Kefarmasian RI No 73 Tahun 2016.Kata Kunci: Standar Pelayanan Kefarmasian, Pelayanan informasi obat, Resep Isoniazid.
Ekstrak Daun Kersen (Muntingia calabura L.) Meningkatkan Konsentrasi GLUT 4 pada Tikus Jantan yang Diinduksi Streptozotosin-Nikotinamida Ramadhiani, Aninditha Rachmah; Tari, Mayang; Pratiwi, Galih; Janadia, Putri Eka; Pratiwi, Jessica Wahyu
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 12 No. 1 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v12i1.16948

Abstract

Diabetes Mellitus (DM) is a group of metabolic diseases characterised by hyperglycaemia, resulting from abnormalities in insulin secretion, insulin action, or both. Kersen (Muntingia calabura L.) leaves contain bioactive compounds, namely flavonoids, tannins, terpenoids, saponins, and polyphenols, which exhibit antioxidants and anti-diabetics. Glucose transporter (GLUT) 4 is an insulin-responsive glucose transporter in muscle and adipose tissue. This study aimed to examine the effect of Kersen leaves extract on GLUT 4 concentration in male rats induced by Streptozotocin-Nicotinamide. Diabetic rats were induced by Streptozotocin 45 mg/kg BW-Nicotinamide 110 mg/kg BW intraperitoneally, and the extract was administered orally for 14 days. Blood glucose level was measured using the Glucose Oxidase-Phenol 4-Aminoantipyrine (GOD-PAP) method, and GLUT 4 activity was assessed using the ELISA method. Statistical results showed significant differences (p<0.05) at 200, 400, and 600 mg/kg BW doses on the glucose and GLUT 4 levels. The 600 mg/kg BW group dose showed the best result with a blood glucose level of 88.22±2.31 mg/dL and a GLUT 4 level of 37.21±0.81 ng/mL. These findings demonstrate that Kersen leaves ethanol extract effectively lowers blood glucose levels and enhances GLUT 4 activity, with the most effective dose being 600 mg/kg BW.
Co-Authors Delina, Susanti Galih Pratiwi, Galih Janadia, Putri Eka Pratiwi, Jessica Wahyu Rosita, Meri Ruliyani, Iqlima Sonlimar mangunsong Tari, Mayang Vera Astuti, Vera