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SOFNIE MARUSIN CHAIRUL
Center for the Application of Isotope and Radiation Technology, National Nuclear Energy Agency (BATAN), Jakarta,12440.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

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Phagocytosis Effectivity Test of Phenylbutenoid Compounds Isolated from Bangle (Zingiber cassumunar Roxb.) Rhizome CHAIRUL CHAIRUL; PRAPTIWI PRAPTIWI; SOFNIE MARUSIN CHAIRUL
Biodiversitas Journal of Biological Diversity Vol. 10 No. 1 (2009)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d100108

Abstract

This study was conducted to determine the immunostimulant activity of several phenylbutenoid derivatives isolated frombangle (Zingiber cassumunar Roxb) rhizome: [1] [(E)-4-(3’,4’-dimethoxyphenyl)but-3-en-1-ol], [2] [(E)-4-(2’,4’,5’ trimethoxyphenyl) but-3-en-1-ol] and [3] [(E)-4-(3’,4’,1-trimethoxyphenyl)but-3-en-1-ol]. Immunostimulant activity was done by stimulating macrophage cells of mouse peritoneum. The result showed that [(E)-4-(3’,4’-dimethoxyphenyl)but 3-en-1-ol] compound had highest immunostimulant activity (99.0%) compared to compound 2 (93.7%) and 3 (80.0%).Key words: Zingiber cassumunar Roxb, immunostimulant, phenylbutenoid derivative, [(E)-4-(3’,4’-dimethoxyphenyl)but-3-en-1-ol], [(E)-4-(2’,4’,5’-trimethoxyphenyl)but-3-en-1-ol]and [(E)-4-(3’,4’,1-trimethoxy phenyl)but-3-en-1-ol
Co-Authors CHAIRUL CHAIRUL PRAPTIWI PRAPTIWI