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All Journal Pharmaciana: Jurnal Kefarmasian SANITAS: Jurnal Teknologi dan Seni Kesehatan
Nugroho, Priyanto Dwi
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Environmental Science Health Professions Medicine & Pharmacology Public Health

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Formulation Antiseptics Artisan Soap From Extract Secang Wood (Caesalpinia sappan L.) And Kaffir Lime Leaves (Citrus hystrix DC.) Nugroho, Priyanto Dwi; Latirah, Latirah; Irwandi, Dodi
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 14 No 2 (2023): SANITAS Volume 14 Nomor 2 Tahun 2023
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2023.407

Abstract

Solid soap as a body skin cleanser can be used as a souvenir. Kaffir lime leaves and sappanwood are natural ingredients and contains good anti-bacterial compound. This paper aims to explain how to make solid soap with shape of watermelon using thick extracts of kaffir lime leaves and sappanwood with a concentration of 1%. Kaffir lime leaf and sappanwood extracts were each made by soaking 300 g of powder in 500 mL pro analysis ethanol solvent for 48 hours and thickening using a rotary evaporator at a temperature of approximately 50 °C. The soap is made using the cold method (cold process). The research results showed that the soap had a fresh smell, solid shape, soft texture and color resembling the shape of a watermelon. Has a pH of 9.8 ± 0.4 and free fatty acids of 1.39 ± 0.2, according SNI Soap. Artisan soap is also antiseptic and able to inhibit Escherichia coli and Staphylococcus aureus bacteria.
Physical, chemical, and microbiological evaluation of antiaging and antibacterial face serum preparations from gotu kola extracts (Centella asiatica L.) Latirah, Latirah; Nugroho, Priyanto Dwi
Pharmaciana Vol. 15 No. 2 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i2.30275

Abstract

The amount of air pollution and unhealthy lifestyles can increase the body's free radicals. Gotu kola herb contains asiaticoside, flavonoids, and compounds with antioxidant activity. To evaluation physical, chemical and microbiological formulation serum-gotu kola extract with 10%, 12%, and 14% concentrations. Evaluation concist of organoleptic, physically, chemically, and microbiologically. Organoleptically, the sample had a fresh smell, greenish color, and soft texture, with pH between 5.0-5.5; specific gravity 1.08 g/mL-1.09 g/mL; spreadability 7.0-7.5 cm; stickiness 1.070 more than 2 minutes; viscosity between 1.200-5.100 cP. The antioxidant test DPPH method had an IC50 value 8.79-20.34 ppm, and the FRAP method had an AAE/g of 0.06099-0.08017 mg AAE/g. The phosphomolybdic method had a value of 6.67-23.17 ppm. The antibacterial analysis of serum formulas showed that S. aureus bacteria were more susceptible than E. coli (p<0.05). This indicates that all formulas have more potent inhibition against Gram-positive bacteria. Conclusion The results obtained showed that all formula had antioxidant activity, antimicrobial activity and meets the physical criteria of face serum. Thus the serum formula at a concentration of extract centella 10%, 12%, and 14% can be used to prepare natural serum, which formula 3 (14%) is the best formula.
Co-Authors Dodi Irwandi, Dodi Latirah, Latirah