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All Journal Biodiversitas Journal of Biological Diversity
ERNAWATI KASIM
Bidang Mikrobiologi, Pusat Penelitian Biologi, Lembaga Ilmu Pengetahuan Indonesia (LIPI), Bogor 16002.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

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Use of local isolate of Monascus purpureus for reducing blood cholesterol in Sprague Dawley rat ERNAWATI KASIM; YETY KURNIAWATI; NOVIK NURHIDAYAT
Biodiversitas Journal of Biological Diversity Vol. 7 No. 2 (2006)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d070206

Abstract

Research using local isolate of M. purpureus to reduce the blood cholesterol total on the white rats of Sprague Dawley strain had been done. The research proposed was to obtain the best doses of fermented rice contain lovastatin to reduce the blood cholesterol content of the white rats Sprague Dawley strain. The research used 42 male rats which was devided into 6 treatments based on the food and fermented rice doses. Each rat was 2 months and 250 gram in weight. The cholesterol food and the standard food given everyday for 20 gram/day/rat. The blood rats was measured the content of cholesterol every seven days for 21 days. The result showed that the lovastatin of the fermented rice could reduce 20,78% the blood cholesterol total of the white rats Sprague Dawley strain. © 2006 Jurusan Biologi FMIPA UNS SurakartaKey words: Monascus purpureus , kolesterol, tikus putih galur Sprague Dawley
Pigment and Lovastatin content on the Red Rice cultivar Bah Butong and BP 1804 IF 9 which Fermented by Monascus purpureus Jmba ERNAWATI KASIM; NANDANG SUHARNA; NOVIK NURHIDAYAT
Biodiversitas Journal of Biological Diversity Vol. 7 No. 1 (2006)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d070103

Abstract

Research on the red rice fermented by Monascus purpureus had been done. The rice consisted of 2 cultivars such as Bah Butong and BP 1804 IF 9. The aim of the research was to know the content of the pigment and lovastatin of the fermentation result/ angkak. Angkak was powdered by using blender. To measure the content of pigment, the powder was extracted by methanol. By using spectrophotometer the content of the pigment could be measured with 390 nm wave lengths for yellow pigment and 500 nm for the red pigment. For lovastatin the powder was extracted by acetonitrile and H2SO4. By using HPLC the content of lovastatin could be measured. The results showed that the highest pigment content for yellow pigment was on the PB 1804 IF 9 cultivar, and red pigment was on the Bah Butong cultivar. The highest lovastatin content was on the BP 1804 IF 9.Key words: Monascus purpureus, red rice, pigment, lovastatin.
Co-Authors NANDANG SUHARNA NOVIK NURHIDAYAT YETY KURNIAWATI