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All Journal Physical Therapy Journal of Indonesia
Afif Rusdiawan
Department of Sport Science, Universitas Negeri Surabaya, Indonesia
Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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High-intensity interval training was more effective than moderate-intensity interval training in lowering creatine kinase and interleukin 6 levels among sports students Resti Nurpratiwi; Andri Suyoko; Afif Rusdiawan; Ariesia Dewi Ciptorini; Muhammad Asrul Sidik; Bhekti Lestari; Fajar Eka Samudra; Yanuar Triardhana; Adi Pranoto; Laily Mita Andriana; I Dewa Made Aryananda Wijaya Kusuma; Rini Ismalasari
Physical Therapy Journal of Indonesia Vol. 6 No. 2 (2025): July-December 2025
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v6i2.253

Abstract

Background: This study aimed to prove that high-intensity interval training (HIIT) is superior to medium-intensity continuous training (MICT) in reducing creatine kinase and interleukin 6 (IL-6) levels in sports students after 4 weeks of exercise. Methods: The study examined the effects of two different training methods—MICT and HIIT. This study included 30 students aged 19-22 years, using a pretest-posttest control group design. Participants were randomly assigned to MICT, HIIT, or control groups (no training) and trained three times a week for four weeks. Creatine and IL-6 levels were analyzed by blood sampling. Data analysis included descriptive statistics, normality tests, and ANOVA tests to evaluate group differences. Results: HIIT was found to be more effective than MICT and the control group in reducing CK and IL-6 levels in sports students after 4 weeks of training (p< 0.001). Conclusion: The HIIT and MICT reduced creatine kinase and IL-6 levels compared to the control group, but HIIT was more effective in reducing creatine kinase and IL-6 levels than MICT in sports students after 4 weeks of exercise.
Co-Authors Adi Pranoto Andri Suyoko Ariesia Dewi Ciptorini Bhekti Lestari Fajar Eka Samudra I Dewa Made Aryananda Wijaya Kusuma Laily Mita Andriana Muhammad Asrul Sidik Resti Nurpratiwi Rini Ismalasari Yanuar Triardhana