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All Journal Mitra Mahajana: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Isniani Ramadhani
Departemen Etik Mediko-Legal (EML), Fakultas Kedokteran, Universitas Pembangunan Nasional “Veteran” Jakarta
Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Education Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health Social Sciences

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ANALISIS HOMA TERHADAP RESISTENSI INSULIN DAN FUNGSISEL β PANKREAS PADA TIKUS WISTAR (Rattus norvegicus) MODEL DIABETES ALOKSAN SETELAH PEMBERIAN EKSTRAK BONGGOLNANAS (Ananas comosus (L.) Merr.) Muhammad Azka Azkiya Arif; Yosha Putri Wahyuni; Isniani Ramadhani; Cut Fauziah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 11 No 1 (2026): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v11i1.2939

Abstract

Diabetes mellitus refers to a metabolic condition characterized by resistance to insulin and abnormalities in pancreatic β-cell function. Pineapple core (Ananas comosus (L.) Merr.) is known to contain bioactive compounds with potential effects on glucose also insulin metabolism. This research aimed to analyze insulin sensitivity using HOMA-IR also HOMA-β in alloxan-induced diabetic Wistar rats (Rattus norvegicus) following administration of pineapple core (Ananas comosus (L.) Merr.) extract. This study employed an experimental laboratory design with a posttest-only control group. Male Wistar rats were induced with alloxan and divided into a control groups and treatment groups receiving graded doses of pineapple core (Ananas comosus (L.) Merr.) extract. Fasting blood glucose levels were measured using a glucometer, while plasma insulin levels were determined using the ELISA method. HOMA-IR and HOMA-β values were calculated to asses insulin sensitivity also pancreatic β- cell function. The results showed a significant difference in HOMA-IR and HOMA- β values between the negative control group and the high dose treatment group (100%) (treatment 3), with a p-value of 0.034. Pineapple core (Ananas comosus (L.) Merr.) extract has the potential to enhance pancreatic β-cell function and significantly improve insulin resistance based on HOMA-IR also HOMA-β parameters in alloxan-induced diabetic Wistar rats.
IMPROVING MOTHERS’ KNOWLEDGE AND AWARENESS OF HELMINTH INFECTION PREVENTION THROUGH BOOKLET-BASED HEALTH EDUCATION AT A COMMUNITY HEALTH CENTRE Dela Riadi; Siti Nuriyatus Zahrah; Isniani Ramadhani
Mitra Mahajana: Jurnal Pengabdian Masyarakat Vol. 7 No. 2 (2026): Volume 7 Nomor 2 Tahun 2026
Publisher : LPPM Universitas Flores

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/mahajana.v7i2.7904

Abstract

Helminth infections remain a significant public health problem in Indonesia, particularly among young children. The high prevalence of helminth infection increases the risk of stunting, anaemia, and malnutrition. Prevention efforts are often hindered by limited public awareness and the misconception that helminth infection is not a serious health issue. This community service program aimed to improve mothers’ knowledge and awareness of helminth infection prevention through booklet-based health education at a community health centre. The participants comprised 12 mothers of young children who visited Community Health Centre X in Depok. The activity was conducted on April 24, 2026, using health counselling, group discussion, and question-and-answer sessions supported by educational booklets. Qualitative evaluation results indicated an improvement in mothers’ understanding of risk factors, transmission, and preventive measures related to helminth infections. In addition, community health volunteers demonstrated increased confidence and readiness to deliver health education to the wider community. In conclusion, booklet-based health education was effective in enhancing mothers’ knowledge and awareness, and community-based educational strategies can support the prevention of helminth infections among young children.
Co-Authors Cut Fauziah Dela Riadi Muhammad Azka Azkiya Arif Siti Nuriyatus Zahrah Yosha Putri Wahyuni