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All Journal Paediatrica Indonesiana Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Madu : Jurnal Kesehatan Cermin Dunia Kedokteran Cermin Dunia Kedokteran
Fadel Bilondatu
Fakultas Kedokteran, Universitas Muhammadiyah Gorontalo
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Public Health

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Profile of Pediatric Nephrotic Syndrome in Wahidin Sudirohusodo Hospital, Makassar, Indonesia Albar, Husein; Bilondatu, Fadel
Cermin Dunia Kedokteran Vol 46, No 3 (2019): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (487.673 KB) | DOI: 10.55175/cdk.v46i3.505

Abstract

Introduction: Nephrotic syndrome is a common and important pediatric chronic renal disease, characterized by massive proteinuria, hypoalbuminemia, edema and hypercholesterolemia. This study was to assess the profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar over a 7-year period. Methods: A retrospective study on hospitalized nephrotic syndrome patients at pediatric nephrology ward in Wahidin Sudirohusodo Hospital Makassar from January 2011 to December 2017. Demographic, clinical and laboratory data were extracted from medical records. Results: A total of 142 children with nephrotic syndrome who fulfilled the inclusion criteria was analyzed. Age at onset ranged from 1.4 to 17.5 years (mean 8.5 years), the majority (66.2%) was 5 year-old and above, predominantly boy (66.2%) with a boy to girl ratio of 1,95:1 and well-nourished (56.3%). Upper respiratory infections were observed in 36.6% cases. The predominant clinical signs and symptoms were edema (100%), hypertension (26.8%). Patients with relapse were 56.3%, and the mortality was 2.12%. The prevalent laboratory findings were microscopic hematuria (50.7%), massive proteinuria (100%), hypoalbuminemia (100%), hypercholesterolemia (100%), and elevated serum creatinine (9.9%). Conclusion: The profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar was similar to typical children nephrotic syndrome and did not significantly differ from other studies.Introduksi : Sindrom nefrotik adalah penyakit kronis anak yang sering dan penting di seluruh dunia, ditandai oleh proteinuria masif, hipoalbuminemia, edema dan hiperkolesterolemia. Studi ini untuk menentukan profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar. Metode : Penelitian retrospektif 7 tahun pada pasien sindrom nefrotik di bangsal nefrologi anak rumah sakit Wahidin Sudirohusodo Makassar dari bulan Januari 2011 sampaidengan Desember 2017. Data diambil dari rekam medik terdiri dari data demografi dan temuan klinis dan laboratorium. Hasil: Total 142 pasien sindrom nefrotik anak yang memenuhi kriteira inklusi dianalisis. Umur pasien saat onset mulai dari 1,4 sampai dengan 17,5 tahun dengan rerata umur 8,5 tahun. Kebanyakan berumur 5 tahun atau lebih (66.2%) didominasi pasien laki-laki (66,2%) dengan rasio jenis kelamin 1,95:1. Status gizi baik (56,3%). Infeksi saluran napas atas ditemukan pada 36,6% kasus. Gejala dan tanda klinis utama adalah edema (100%), hipertensi (26,8%), Relaps pada 56,3% kasus dan 2,12% pasien meninggal. Temuan laboratorium utama adalah hematuria mikroskopik (50,7%), proteinuria masif (100%), hipoalbuminemia (100%), hiperkolesterolemia (100%), dan peningkatan kreatinin serum (9,9%). Simpulan: Profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar pada umumnya serupa dan tidak berbeda bermakna dari penelitian lain. 
Risk factors for relapse in pediatric nephrotic syndrome Husein Albar; Fadel Bilondatu; Dasril Daud
Paediatrica Indonesiana Vol 58 No 5 (2018): September 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.04 KB) | DOI: 10.14238/pi58.5.2018.238-41

Abstract

Background Nephrotic syndrome (NS) is the most common kidney disease in children and is characterized by edema, massive proteinuria, hypoalbuminemia, and hyperlipidemia. High relapse rate remains a major problem in the management of this syndrome. Objective To identify risk factors for relapse in pediatric nephrotic syndrome. Methods This study was carried out in the Wahidin Sudirohusodo Teaching Hospital in Makassar, South Sulawesi, Indonesia, from January to August 2017 using complete medical records of children diagnosed with NS. Subjects were divided into 2 groups: 1) relapsed NS or 2) non-relapsed NS. The following potential risk factors for relapse were analyzed using Chi-square test: age, sex, nutritional status, hypertension, serum creatinine level, and infection at the time of established diagnosis of NS. Results A total of 142 children with NS who fulfilled the inclusion criteria aged 1.4 to 17.5 years were included in the study. Subjects were mostly boys (66.2%), with a male: female ratio of 1.95:1. The relapsed NS group had 80 cases (56.3%) and the non-relapsed NS group had 62 cases (43.7%). Statistical analysis revealed that nutritional status was a significant risk factor for relapse in pediatric nephrotic syndrome (P<0.05). Conclusion Nutritional status is an independent risk factor for relapse in pediatric nephrotic syndrome.
Profile of Pediatric Nephrotic Syndrome in Wahidin Sudirohusodo Hospital, Makassar, Indonesia Husein Albar; Fadel Bilondatu
Cermin Dunia Kedokteran Vol 46, No 3 (2019): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.505

Abstract

Introduction: Nephrotic syndrome is a common and important pediatric chronic renal disease, characterized by massive proteinuria, hypoalbuminemia, edema and hypercholesterolemia. This study was to assess the profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar over a 7-year period. Methods: A retrospective study on hospitalized nephrotic syndrome patients at pediatric nephrology ward in Wahidin Sudirohusodo Hospital Makassar from January 2011 to December 2017. Demographic, clinical and laboratory data were extracted from medical records. Results: A total of 142 children with nephrotic syndrome who fulfilled the inclusion criteria was analyzed. Age at onset ranged from 1.4 to 17.5 years (mean 8.5 years), the majority (66.2%) was 5 year-old and above, predominantly boy (66.2%) with a boy to girl ratio of 1,95:1 and well-nourished (56.3%). Upper respiratory infections were observed in 36.6% cases. The predominant clinical signs and symptoms were edema (100%), hypertension (26.8%). Patients with relapse were 56.3%, and the mortality was 2.12%. The prevalent laboratory findings were microscopic hematuria (50.7%), massive proteinuria (100%), hypoalbuminemia (100%), hypercholesterolemia (100%), and elevated serum creatinine (9.9%). Conclusion: The profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar was similar to typical children nephrotic syndrome and did not significantly differ from other studies.Introduksi : Sindrom nefrotik adalah penyakit kronis anak yang sering dan penting di seluruh dunia, ditandai oleh proteinuria masif, hipoalbuminemia, edema dan hiperkolesterolemia. Studi ini untuk menentukan profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar. Metode : Penelitian retrospektif 7 tahun pada pasien sindrom nefrotik di bangsal nefrologi anak rumah sakit Wahidin Sudirohusodo Makassar dari bulan Januari 2011 sampaidengan Desember 2017. Data diambil dari rekam medik terdiri dari data demografi dan temuan klinis dan laboratorium. Hasil: Total 142 pasien sindrom nefrotik anak yang memenuhi kriteira inklusi dianalisis. Umur pasien saat onset mulai dari 1,4 sampai dengan 17,5 tahun dengan rerata umur 8,5 tahun. Kebanyakan berumur 5 tahun atau lebih (66.2%) didominasi pasien laki-laki (66,2%) dengan rasio jenis kelamin 1,95:1. Status gizi baik (56,3%). Infeksi saluran napas atas ditemukan pada 36,6% kasus. Gejala dan tanda klinis utama adalah edema (100%), hipertensi (26,8%), Relaps pada 56,3% kasus dan 2,12% pasien meninggal. Temuan laboratorium utama adalah hematuria mikroskopik (50,7%), proteinuria masif (100%), hipoalbuminemia (100%), hiperkolesterolemia (100%), dan peningkatan kreatinin serum (9,9%). Simpulan: Profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar pada umumnya serupa dan tidak berbeda bermakna dari penelitian lain. 
Profile of Pediatric Nephrotic Syndrome in Wahidin Sudirohusodo Hospital, Makassar, Indonesia Husein Albar; Fadel Bilondatu
Cermin Dunia Kedokteran Vol. 46 No. 3 (2019): Nutrisi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.494

Abstract

Introduction: Nephrotic syndrome is a common and important pediatric chronic renal disease, characterized by massive proteinuria, hypoalbuminemia, edema, and hypercholesterolemia. This study was to assess the profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar over a 7-year period. Methods: A retrospective study on hospitalized nephrotic syndrome patients at pediatric nephrology ward in Wahidin Sudirohusodo Hospital Makassar from January 2011 to December 2017. Demographic, clinical, and laboratory data were extract from medical records. results: Total 142 children with nephrotic syndrome who fulfilled the inclusion criteria were analyze. Age at onset ranged from 1.4 to 17.5 years (mean 8.5 years), the majority (66.2%) was 5 year-old and above, predominantly boy (66.2%) with a boy to girl ratio of 1,95:1 and well-nourished (56.3%). Upper respiratory infections were observed in 36.6% cases. The predominant clinical signs and symptoms were edema (100%), hypertension (26.8%). Patients with relapse were 56.3%, and the mortality was 2.12%. The prevalent laboratory findings were microscopic hematuria (50.7%), massive proteinuria (100%), hypoalbuminemia (100%), hypercholesterolemia (100%), and elevated serum creatinine (9.9%). conclusion: The profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar was similar to typical children nephrotic syndrome and did not significantly differ from other studies. Introduksi: Sindrom nefrotik adalah penyakit kronis anak yang sering dan penting di seluruh dunia, ditandai oleh proteinuria masif, hipoalbuminemia, edema, dan hiperkolesterolemia. Studi ini untuk menentukan profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar selama 7 tahun. Metode: Penelitian retrospektif pada pasien sindrom nefrotik di bangsal nefrologi anak rumah sakit Wahidin Sudirohusodo Makassar dari bulan Januari 2011 sampai dengan Desember 2017. Data diambil dari rekam medik terdiri dari data demografi dan temuan klinis dan laboratorium. Hasil: Total 142 pasien sindrom nefrotik anak yang memenuhi kriteira inklusi dianalisis. Umur pasien saat onset mulai dari 1,4 sampai dengan 17,5 tahun dengan rerata umur 8,5 tahun. Kebanyakan berumur 5 tahun atau lebih (66.2%) didominasi pasien laki-laki (66,2%) dengan rasio jenis kelamin 1,95:1. Status gizi baik (56,3%). Infeksi saluran napas atas ditemukan pada 36,6% kasus. Gejala dan tanda klinis utama adalah edema (100%), hipertensi (26,8%), relaps pada 56,3% kasus, dan 2,12% pasien meninggal. Temuan laboratorium utama adalah hematuria mikroskopik (50,7%), proteinuria masif (100%), hipoalbuminemia (100%), hiperkolesterolemia (100%), dan peningkatan kreatinin serum (9,9%). simpulan: Profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar pada umumnya serupa dan tidak berbeda bermakna dari penelitian lain
PROFIL KLINIS BAYI BERAT LAHIR RENDAH DI NICU RSUD DR. HASRI AINUN HABIBIE GORONTALO Bilondatu, Fadel; Nabila Rizki Sakinah
Medika Alkhairaat: Jurnal Penelitian Kedokteran dan Kesehatan Vol 6 No 3 (2024): Desember
Publisher : Fakultas Kedokteran Universitas Alkhairaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31970/ma.v6i3.260

Abstract

ABSTRAK Bayi berat badan lahir rendah (BBLR) merupakan masalah kesehatan yang membutuhkan perhatian khusus, oleh karena masih meningkatnya angka morbiditas dan mortalitas neonatal. Dengan memahami profil klinis BBLR maka dapat meningkatkan strategi dalam upaya penurunan angka kematian pada neonatal. Studi ini bertujuan untuk mengetahui profil klinis dan faktor penyebab BBLR yang dirawat di Unit Perawatan Intensif Neonatal (NICU) di RSUD dr. Hasri Ainun Habibie, Gorontalo. Desain penelitian menggunakan studi cross-sectional dengan menggunakan data rekam medis dari 191 bayi yang dirawat di NICU. Data tersebut meliputi berat lahir, usia kehamilan, usia ibu, dan paritas. Analisis statistik digunakan untuk mengeksplorasi hubungan antara faktor-faktor ini dan kejadian BBLR. Hasil dari studi ini melaporkan bahwa 32% termasuk BBLR dengan berat lahir ≤ 2500 gram. Hubungan yang signifikan secara statistik antara usia kehamilan dan terjadinya LBW (p < 0,001). Sebaliknya, tidak ada korelasi signifikan yang diamati antara BBLR dan faktor ibu seperti paritas dan usia. Dari hasil penelitian ini disarankan pentingnya perawatan prenatal yang terfokus dalam mencegah persalinan prematur dan menurunkan insiden BBLR secara efektif di wilayah tersebut. ABSTRACT Low birth weight (LBW) infant is a significant public health concern, often linked to increased neonatal morbidity and mortality. Understanding the clinical profile of LBW infants can inform strategies to improve neonatal outcomes. This study aims to investigate the clinical profile and associated factors of LBW infants admitted to the Neonatal Intensive Care Unit (NICU) at RSUD dr. Hasri Ainun Habibie, Gorontalo, from January to April 2024. A cross-sectional descriptive study was conducted using medical record data from 191 infants admitted to the NICU. The data included birth weight, gestational age, maternal age, and parity. Statistical analysis was used to explore the associations between these factors and the incidence of LBW. This study reported that 32% of infants had a birth weight of less than 2500 grams, classifying them as low birth weight (LBW). A statistically significant association was identified between gestational age and the occurrence of LBW (p < 0.001). In contrast, no significant correlations were observed between LBW and maternal factors such as parity and age. Gestational age emerged as a primary determinant of LBW in this study, highlighting the crucial importance of prenatal care in preventing preterm deliveries and lowering the incidence of LBW. Maternal age and parity were not found to have a significant influence, indicating the need for focused prenatal interventions to effectively address this issue in the region
Profile of Pediatric Nephrotic Syndrome in Wahidin Sudirohusodo Hospital, Makassar, Indonesia Husein Albar; Fadel Bilondatu
Cermin Dunia Kedokteran Vol 46 No 3 (2019): Nutrisi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.494

Abstract

Introduction: Nephrotic syndrome is a common and important pediatric chronic renal disease, characterized by massive proteinuria, hypoalbuminemia, edema, and hypercholesterolemia. This study was to assess the profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar over a 7-year period. Methods: A retrospective study on hospitalized nephrotic syndrome patients at pediatric nephrology ward in Wahidin Sudirohusodo Hospital Makassar from January 2011 to December 2017. Demographic, clinical, and laboratory data were extract from medical records. results: Total 142 children with nephrotic syndrome who fulfilled the inclusion criteria were analyze. Age at onset ranged from 1.4 to 17.5 years (mean 8.5 years), the majority (66.2%) was 5 year-old and above, predominantly boy (66.2%) with a boy to girl ratio of 1,95:1 and well-nourished (56.3%). Upper respiratory infections were observed in 36.6% cases. The predominant clinical signs and symptoms were edema (100%), hypertension (26.8%). Patients with relapse were 56.3%, and the mortality was 2.12%. The prevalent laboratory findings were microscopic hematuria (50.7%), massive proteinuria (100%), hypoalbuminemia (100%), hypercholesterolemia (100%), and elevated serum creatinine (9.9%). conclusion: The profile of pediatric nephrotic syndrome at Wahidin Sudirohusodo Hospital Makassar was similar to typical children nephrotic syndrome and did not significantly differ from other studies. Introduksi: Sindrom nefrotik adalah penyakit kronis anak yang sering dan penting di seluruh dunia, ditandai oleh proteinuria masif, hipoalbuminemia, edema, dan hiperkolesterolemia. Studi ini untuk menentukan profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar selama 7 tahun. Metode: Penelitian retrospektif pada pasien sindrom nefrotik di bangsal nefrologi anak rumah sakit Wahidin Sudirohusodo Makassar dari bulan Januari 2011 sampai dengan Desember 2017. Data diambil dari rekam medik terdiri dari data demografi dan temuan klinis dan laboratorium. Hasil: Total 142 pasien sindrom nefrotik anak yang memenuhi kriteira inklusi dianalisis. Umur pasien saat onset mulai dari 1,4 sampai dengan 17,5 tahun dengan rerata umur 8,5 tahun. Kebanyakan berumur 5 tahun atau lebih (66.2%) didominasi pasien laki-laki (66,2%) dengan rasio jenis kelamin 1,95:1. Status gizi baik (56,3%). Infeksi saluran napas atas ditemukan pada 36,6% kasus. Gejala dan tanda klinis utama adalah edema (100%), hipertensi (26,8%), relaps pada 56,3% kasus, dan 2,12% pasien meninggal. Temuan laboratorium utama adalah hematuria mikroskopik (50,7%), proteinuria masif (100%), hipoalbuminemia (100%), hiperkolesterolemia (100%), dan peningkatan kreatinin serum (9,9%). simpulan: Profil sindrom nefrotik anak di rumah sakit Wahidin Sudirohusodo Makassar pada umumnya serupa dan tidak berbeda bermakna dari penelitian lain
Penggunaan Aplikasi Berbasis Internet Dalam Pemantauan Status Gizi Anak Stunting Di Posyandu Desa Tabumela, Kabupaten Gorontalo Fadel Bilondatu; Ainun Dwi Silfani S. Dukalang; Anugrah Haq
Madu Jurnal Ilmu Kebidanan Vol 15, No 1: Juni 2026
Publisher : Program Studi DIV Kebidanan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31314/mjk.15.1.31-40.2026

Abstract

Growth monitoring for stunted children at community health posts often faces practical barriers, including manual recording, delayed reporting, and inconsistent follow-up. Internet-based applications may help address these problems, but local evidence on their use in stunted children remains limited. This study aimed to assess the use of an Internet-based application for monitoring the nutritional status of stunted children at community health posts in Gorontalo Province. A mixed methods design with an explanatory sequential approach was used. The quantitative component used a quasi-experimental pre-post design with two groups of participants. Twenty stunted children from posyandu were assigned to an intervention group (n=10) receiving application-based monitoring and a control group (n=10) receiving conventional monitoring. The measurements were conducted in October-November 2025. The qualitative component involved five respondents through in-depth interviews. As a preliminary study, the findings indicate that application use was associated with a difference in HAZ change patterns between groups (delta HAZ: +0.100 vs −0.175; p=0.040; Cohen’s d=0.99). These findings are hypothesis-generating and require confirmation in larger randomized studies. Interviews indicated that the application was generally well accepted, although its use was still influenced by the condition of anthropometric equipment, cadres’ skills, internet costs, and follow-up from health services. All measurements and data entry were performed independently by cadres without researcher intervention, reflecting real-world use conditions; this also represents a limitation as there was no external validation of input accuracy.
Co-Authors Ainun Dwi Silfani S. Dukalang Anugrah Haq Dasril Daud Husein Albar Husein Albar Husein Albar Husein Albar, Husein Nabila Rizki Sakinah