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All Journal Cermin Dunia Kedokteran
Nasution, Ibrahim Irsan
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Health Professions

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Odinofagia diduga disebabkan oleh penyempitan esofagus akibat konsumsi glifosat-surfaktan dalam jumlah kecil: Laporan Kasus Simanjuntak, Arya Marganda; -, Harianto; Nasution, Ibrahim Irsan
Cermin Dunia Kedokteran Vol 53 No 07 (2026): Juli 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i07.1872

Abstract

Introduction: Glyphosate-surfactant is a non-selective, broad-spectrum systemic herbicide widely used in agriculture, forestry, and industry. It is frequently ingested in suicide attempt and depending on the ingested dose, may cause local caustic injury, systemic toxicity, or even death. Case: A 32-year-old man presented to the emergency department (ED) with throat pain and difficulty swallowing food for 2 days after ingesting approximately 5 mL of glyphosate-surfactant. Examination found hyperemic pharyngeal arch and oropharynx edema (Mallampati III). Laboratory results revealed leukocytosis, renal function, and electrolyte abnormalities. After gastric lavage, antibiotics, NSAIDs, and a liquid diet, the patient improved and was able to eat independently. Discussion: Even in small volumes (5 mL), glyphosate-surfactant, a caustic substance, can cause irritation and inflammation of the esophageal tract and progress to esophageal stricture. Conclusion: Small amounts of glyphosate-surfactant compound ingestion caused esophageal strictures, affecting the patient's ability to eat and causing discomfort, despite no kidney or respiratory damage.
Co-Authors Harianto - Simanjuntak, Arya Marganda