<![CDATA[Background: Geriatricians undergo an aging process involving molecular and cellular changes that lead to physiological changes. These changes have led to the emergence of comorbidities suffered by 44% of geriatricians in Indonesia, such as hypertension, diabetes mellitus, chronic pulmonary obstruction, and others. Changing conditions during old age and comorbid factors affect a person's quality of life, especially in the geriatric population. This is a challenge for medical practitioners who will carry out anesthesia procedures. Quality of life is an important measure in assessing the success of patient treatment, especially geriatric patients with comorbidities undergoing anesthesia and operative procedures.Objective: To determine the association between comorbid conditions and the quality of life of geriatric patients undergoing anesthesia procedures at Dr. Sardjito Hospital.Methods: A retrospective observational study was conducted on secondary data of geriatric patients who underwent anesthesia at Dr Sardjito Hospital, Yogyakarta, in February-April 2021. Quality of life was measured using the Indonesian WHOQoL-BREF instrument, while comorbidity was measured using the Charlson Comorbidity Index (CCI) instrument. Association between CCI and WHOQoL-BREF was analyzed using the chi-square test, while multivariate analysis was carried out using logistic regression. ROC analysis was also carried out to determine the optimal cut-off point for the CCI score in predicting poor quality of life.Results: The ROC graph shows that the cut-off score CCI=1 with a sensitivity of 64.4% and a specificity of 58.0% can predict WHOQoL-BREF <60, but with poor discrimination ability (AUC 0.612; 95% CI 0.515 – 0.709).]]>
