Efforts to maintain the health of infants and children should be aimed at preparing the next generation to be healthy, intelligent, and qualified and to reduce infant and child mortality. The provision of basic immunization is useful to provide comprehensive protection against dangerous diseases. Immunization is one way to prevent infectious diseases, especially diseases that can be prevented by immunization (PD3I). The design of this study is a systematic review. The search for articles discussed in this study uses several databases, including Pubmed, Science Direct, and Google Scholar, with a time span of 2019 to 2022. The keywords used to search for the article are "complete immunization" or "complete vaccination" and "immunization acceptance" and determinants or predictors or "risk factors" or causes and children or "under 2 years" or "12–23 months. The type of article used is a research article. The collected articles are then re-selected using inclusion criteria, namely: The collected articles are then re-selected using inclusion criteria, namely: 1) the purpose of the article is to analyze the receipt of complete immunization in children, 2) to analyze the factors that affect complete immunization, as well as exclusion criteria, namely 1) it is not a full-text article, 2) the article does not use English. Factors that affect the completeness of advanced immunization include factors such as knowledge, education, age, occupation, attitude, family support, distance to health services.