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AMPICILLIN SULBACTAM AND CEFOTAXIME ARE SIMILARLY EFFECTIVE IN PEDIATRIC PNEUMONIA Puspitasari, Diny; Hasmono, Didik; Rahman, Taufiqur
Folia Medica Indonesiana Vol. 52 No. 2 (2016): APRIL - JUNE 2016
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (178.598 KB) | DOI: 10.20473/fmi.v52i2.5225

Abstract

Pneumonia is an infection of the lungs that occurs and still cause high mortality in young children today. The main cause is bacterial or viral. Antibiotics still recommended though it is difficult to know the cause is bacterial or viral. Ampicillin be the first option some guideline. Increased resistance worldwide become one of them concerns the effectiveness of antibiotics. The main treatment of toddler pneumonia in Muhammadiyah Hospital Lamongan are ampicillin sulbactam and cefotaxime. The study was conducted to analyze the effectiveness of both antibiotics. This study aims to analyze comparison in the use of ampicillin sulbactam and cefotaxime pneumonia patients aged 3-59 months from November 2013 to March 2014. Patients who met the inclusion criteria were prospectively observed for clinical data, laboratory data, the data microbiology. After it is analyzed to know the difference between the effectiveness of antibiotics. In this study of 29 patients included in the inclusion criteria, 17 patients who received antibiotics ampicillin sulbactam and 12 patients receiving cefotaxime. In the comparison of the mean pulse pulse is known there is a significant reduction in both groups of patients on the second day and was not significantly different between the two groups (p = 0.084). Likewise, the average ratio of temperature (p = 0.117), breath rate (p = 0.839), leukocytes of patients (p = 0.429). Length of stay for ampicillin sulbactam group was 4.77 days and 5.17 days for cefotaxime group. Analysis showed no differences between the two groups for lenght (p = 0.275). Of the 22 patients who were sampled for blood culture examination only 1 patient with positive results. Based on these results we can conclude that ampicillin sulbactam and cefotaxime effective in cases of children pneumonia, and there is no distinction based on the parameters in body temperature, breath rate, pulse, leukocytes and long hospitalization of patients. Regimentation dosage is appropriate based on guidelines, and length of stay less than 10 days. Found no side effects of both drugs.
PERAN INTERVENSI APOTEKER DALAM KEPATUHAN MINUM OBAT PASIEN HIPERTENSI: TINJAUAN SISTEMATIS Akri, Yusnita Julyarni; Puspitasari, Diny
ASSYIFA : Jurnal Ilmu Kesehatan Vol. 3 No. 2 (2025)
Publisher : Forind Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62085/ajk.v3i2.152

Abstract

One of the factors that often hinders medication adherence is unwanted side effects or interactions with other medications that are being used. Pharmacists have in-depth knowledge of pharmacology and drug interactions, so they can provide information to patients on how to manage those side effects. This study aims to systematically review the role of pharmacists in medication adherence of hypertensive patients. The literature search will be carried out in March 2025. Systematic reviews are carried out by searching for articles from Google Scholar. Keywords for searching this article include "intervention" or "pharmacist" or "compliance" or "taking medication" or "hypertension". Of the 580 articles collected through an initial search on Google Scholar, the author identified 4 articles regarding the role of pharmacists in medication adherence of hypertensive patients. Adherence to medication in hypertensive patients is essential to control blood pressure and prevent further complications. Pharmacists have a very strategic role in improving patient compliance by providing clear education, monitoring medication use, dealing with side effects, providing motivational support, and collaborating with other health workers.