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All Journal Al-MIKRAJ: Jurnal studi Islam dan Humaniora International Journal of Public Health Excellence (IJPHE) Vitamedica: Jurnal Rumpun Kesehatan Umum
Muhammad Gunawan
Sekolah Tinggi Ilmu Kesehatan Indah Medan, Indonesia
Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Uji Potensi Antituberkulosis Ekstrak N-Heksan dan Ekstrak Etanol Daun Jeruk Nipis (Citrus Aurantiifolia) secara in Vitro Alya Rosandiyus Putri; Cut Fatimah; Muhammad Gunawan; Safriana Safriana
AL-MIKRAJ Jurnal Studi Islam dan Humaniora (E-ISSN 2745-4584) Vol. 5 No. 01 (2024): AL-Mikraj Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6181

Abstract

Tuberculosis is a disease caused by Mycobacterium tuberculosis which is widely suffered and causes death. Currently, antituberculosis treatment using synthetic chemicals has been widely resistant. The purpose of this study was to test the potential of lime extract to inhibit the growth of tuberculosis bacteria. This research method uses a quantitative approach and is experimental. The results of the study showed that the results of the phytochemical screening test showed the same group of chemical compounds in fresh leaves, simplex and ethanol extract of lime leaves, namely alkaloids, flavonoids, tannins, saponins, steroids and glycosides. While the n-hexane extract only contains steroids and glycosides. Then the effectiveness of antituberculosis can be seen from the ethanol extract being stronger than the n-hexane extract, namely in the 1st week there was inhibition while the n-hexane extract from the 1st week to the 4th week had bacterial growth.
Formulasi Hair Tonic Ekstrak Etanol Kulit Buah Pepaya (Carica Papaya L.) dan Uji Efektivitas Pertumbuhan Rambut pada Marmut Jantan (Cavia porcellus) Mella Candani; Muhammad Gunawan; Siti Aisyah Tanjung; Muhammad Bagas
AL-MIKRAJ Jurnal Studi Islam dan Humaniora (E-ISSN 2745-4584) Vol. 5 No. 01 (2024): AL-Mikraj Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6198

Abstract

Hair for humans has an important role, in addition to protecting the skin from adverse environments, hair also plays an important role in a person's appearance. Losing a lot of hair due to hair loss can cause a lack of self-confidence, disappointment, and frustration, so it must be addressed immediately so as not to worsen the condition that can cause baldness. This study aims to determine whether there is a content of secondary metabolite compounds in fresh herbal medicine, herbal medicine powder and ethanol extract of papaya fruit skin; ethanol extract of papaya fruit skin (Carica papaya L.) can be formulated in the form of hair tonic preparations; whether the difference in concentration of ethanol extract of papaya fruit skin (Carica papaya L.) provides different activities in triggering hair growth in guinea pigs. This research method uses a quantitative approach and is experimental with independent variables, namely papaya fruit skin, herbal medicine, and ethanol extract of papaya fruit skin with concentrations of 10%, 20%, 30%. Research stages: phytochemical screening of fresh papaya fruit peel, powdered simplicia and ethanol extract, hair tonic formulation containing ethanol extract of papaya fruit peel 10%, 20% and 30%, hair tonic evaluation includes: organoleptic, viscosity, stability, pH, irritation, and preference test. And hair growth activity test on male guinea pigs. The results showed that the ethanol extract of papaya fruit peel contains alkaloids, flavonoids, saponins, steroids, and glycosides, can be formulated into hair tonic (EEKP) that meets physical quality requirements. Hair tonic EEKP 30% is the best because it has high hair growth activity, which is an average of 16.375 mm where this EEKP 30% hair tonic has almost the same hair growth activity as the positive control, which is an average of 16.782 mm.
Penetapan Kadar Besi dan Seng Air Sumur Gali dan Sumur Bor pada Daerah Lenggadai Hilir secara Spektrofotometri Serapan Atom Laila Anwar; Cut Fatimah; Muhammad Bagas F; Muhammad Gunawan
AL-MIKRAJ Jurnal Studi Islam dan Humaniora (E-ISSN 2745-4584) Vol. 5 No. 01 (2024): AL-Mikraj Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6302

Abstract

Many people in Lenggadai Hilir Village, Rimba Melintang District, Rokan Hilir Regency, Riau use dug well water and drilled well water as clean water, drinking water and household needs that look cloudy, colored and slightly odorous, possibly containing metals such as Fe and Zn. The content of Fe and Zn metals in clean water has the requirements of the Regulation of the Minister of Health of the Republic of Indonesia Number 416 / Menkes / PER / IX / 1990, namely a maximum of 1.0 mg / l Fe and a maximum of 15 mg / l Zn. The purpose of this study was to determine the levels of Fe and Zn in the water used by the population. This research method is descriptive quantitative. Determination of Fe and Zn levels in water samples in the village was carried out using Atomic Absorption Spectrophotometry (AAS), which were previously destroyed with nitric acid. Before determining the levels, it began with an identification test with several chemical reactions to ensure the presence of Fe and Zn content in the samples. The results showed that all samples tested contained Fe and Zn. All samples of drilled wells contain Fe, the levels of which do not meet the requirements and all Zn samples meet the requirements, from 8 dug well samples there are 6 dug well samples contaminated with Fe, namely dug well 1 (1), dug well 1 (2), dug well 2 (1), dug well 2 (2), dug well 3 (1) and dug well 3 (2). Thus, the water used by the community as clean water and household needs should not be used for household water needs and drinking water before processing and filtering before consumption.
Diuretic Effectiveness Test of Leucare Leucabeth (Leucaena leucocephala (Lam.) de Wit) Ethanol Extract on Male White Rats (Rattus norvegicus) Muhammad Gunawan; Siti Aisyah Tanjung; Enny Fitriani
International Journal of Public Health Excellence (IJPHE) Vol. 5 No. 1 (2025): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v5i1.1535

Abstract

Leucaena leucaena seeds are widely believed to be a plant that can treat various ailments, including diuretics. Leucaena seeds contain a high amount of alkaloids, saponins, flavonoids, tannins, protein, fat, calcium, phosphorus, iron, amino acids, and leucanol. The purpose of this study was to determine whether ethanol extract of leucaena seeds can have a diuretic effect on male white rats. This study used 30 male white rats divided into five groups: Group I (solvent control) with 1% CMC. Group II (comparison) with furosemide. Groups III, IV, and V (treatment) were given ethanol extract of leucaena seeds at doses of 150 mg/kg BW, 300 mg/kg BW, and 600 mg/kg BW, respectively. The test preparations were administered orally using a metabolic cage equipped with a rat urine collector. Observations were made every hour for 8 hours to determine total urine volume. The urine volume of each group was statistically analyzed using ANOVA and the LSD test. The results of the statistical test of urine volume between the furosemide and ethanol extract groups of lamtoro seeds (Leucaena leucocephala (Lam.) de Wit) showed no significant difference. From the results of the study, it can be concluded that the higher the concentration of EEBL suspension given, the more urine volume will be produced, and when the EEBL suspension was given at a dose of 600 mg/kg BW, the results were almost comparable to the group of animals given furosemide suspension.
Formulasi Sediaan Moisturizer Gel Dari Sari Air Buah Pir (Pyrus Communis L.) Dan Uji Efektivitas Sebagai Pelembab Olivia Anggrella; Melati Yulia Kusumastuti; Enny Fitriania; Muhammad Gunawan
VitaMedica : Jurnal Rumpun Kesehatan Umum Vol. 4 No. 4 (2026): Oktober : VitaMedica : Jurnal Rumpun Kesehatan Umum
Publisher : STIKES Columbia Asia Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62027/vitamedica.v4i4.1070

Abstract

Dry skin is a common dermatological problem caused by decreased water content in the stratum corneum. Natural ingredients rich in water and secondary metabolites are being explored as alternatives to synthetic moisturizers. This study aimed to formulate a moisturizer gel containing pear fruit juice (Pyrus communis L.) at 5%, 10%, and 15% concentrations and to evaluate its physical characteristics and moisturizing effectiveness. The study was designed as a laboratory experiment. Pear juice was extracted from fresh fruit, screened for secondary metabolites, and formulated into four gels (F0 blank; F1–F3 containing 5%, 10%, and 15% pear juice) using carbopol as the gelling agent. Physical evaluation included organoleptic, homogeneity, pH, adhesion, spreadability, and irritation tests on six volunteers. Skin moisture was measured on six volunteers per formula over four weeks using a skin analyzer. Phytochemical screening detected alkaloids, flavonoids, tannins, glycosides, saponins, and steroids/triterpenoids. All formulas were homogeneous, non-irritant, had pH between 5.8 and 6.2, adhesion above 4 seconds, and spreadability between 6.2 and 6.7 cm. Mean moisture increase in week four was 37.84% (blank), 49.73% (5%), 56.10% (10%), and 72.11% (15%). The findings indicate that pear juice can be formulated as a moisturizer gel and shows a trend of increasing skin moisture with higher concentrations.
Co-Authors Alya Rosandiyus Putri Cut Fatimah Enny Fitriani Enny Fitriania Laila Anwar Melati Yulia Kusumastuti Mella Candani Muhammad Bagas F Olivia Anggrella Safriana Safriana Siti Aisyah Tanjung