Wima Anggitasari
Universitas dr Soebandi

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Identification of Antibiotic Dose Appropriateness in Patients with Non-Pneumonia Acute Respiratory Tract Infection at Community Health Center X Ayu Putri MS; Handa Riyatul Masruroh; Shinta Mayasari; Wima Anggitasari
Indonesian Pharmacopeia Journal Vol. 2 No. 2 (2026): Volume 2 Nomor 2, 2026
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i2.90

Abstract

An Non-pneumonia acute respiratory tract infection (ARTI) is one of the most common diseases in the community and a frequent cause of patient visits to healthcare facilities. Based on a preliminary study, non-pneumonia ARTI was among the ten most prevalent diseases at Community Health Center X, with 266 reported cases during the period of January–December 2025. The high incidence of non-pneumonia ARTI has led to increased antibiotic use. Therefore, antibiotics should be used rationally, including through appropriate dosing. Inappropriate antibiotic dosing may reduce therapeutic effectiveness and increase the risk of bacterial resistance. This study aimed to identify the appropriateness of antibiotic dosing in patients with non-pneumonia ARTI at Community Health Center X. This study employed a descriptive observational design with a retrospective approach. A total of 160 patients were selected using purposive sampling. Data were collected from the medical records of patients with non-pneumonia ARTI, and the appropriateness of antibiotic dosing was evaluated based on the Community Health Center X Formulary. Data were analyzed using univariate analysis. The results showed that, among the 160 patients with non-pneumonia ARTI, the largest age group was children aged 0–5 years, accounting for 46 patients (28.8%). Amoxicillin was the most frequently prescribed antibiotic (77%), followed by ciprofloxacin (23%). The most commonly prescribed dosage strengths were amoxicillin 500 mg (48.1%), amoxicillin 125 mg (18.8%), and ciprofloxacin 500 mg (23.1%). The most common dosing frequency was three times daily (76.9%), followed by twice daily (23.1%). Evaluation of antibiotic dose appropriateness showed that all 160 patients (100%) received appropriate antibiotic doses. In conclusion, all patients with non-pneumonia ARTI at Community Health Center X received appropriate antibiotic doses.
Analysis of Direct Medical Costs for Inpatients with Chronic Obstructive Pulmonary Disease at Jember Lung Hospital Ayu Putri MS; Devi Rahayu; Shinta Mayasari; Wima Anggitasari
Indonesian Pharmacopeia Journal Vol. 2 No. 2 (2026): Volume 2 Nomor 2, 2026
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i2.91

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory disease characterized by progressive airflow limitation. The goals of COPD therapy are to reduce symptoms, decrease exacerbations, improve quality of life, and reduce mortality (Kristiningrum, 2019). Differences in patient characteristic and disease severity may affect therapeutic needs and the costs incurred by patients. Direct medical cost analysis is one of the components of the Cost Of Illness method used to determine the economic burden of a disease (Andayani, 2022). This study aimed to analyze the direct medical costs of hospitalized COPD patients at Jember Lung Hospital. This study was an observational descriptive study with a retrospective design using secondary data from medical records of COPD patients during the January-October 2025 period. The sampling technique used was total sampling with a total sample of 71 patients. Cost analysis was performed using the Cost Of Illness (COI) method. The results showed that COPD patients were predominantly male with 53 patients (74,65%), aged 60-69 years with 32 patients (45,07%), and had a length of stay of 4-6 days with 40 patients (56,33%). The average medication cost was IDR 986.697, treatment cost was IDR 1.394.451, and laboratory cost was IDR 137.242. The average direct medical cost was IDR 2.518.390, which was lower than the INA-CBG’s tariff of IDR 4.888.400. Treatment cost was the largest cost component contributing to the direct medical costs of hospitalized COPD patients. Key words: COPD; direct medical cost; Cost of Illness; pharmacoeconomics; COPD; hospitalization