National integration is an essential process in maintaining unity and cohesion within Indonesia’s diverse society. In the era of globalization, the rapid flow of information, culture, and technology brings both positive and negative impacts on national integration. This study aims to analyze the various challenges faced in achieving national integration and to examine strategies that can be implemented to strengthen it. The method used in this research is a literature study by reviewing various relevant sources such as books, journals, and scientific articles. The findings reveal that there are three main challenges to national integration in the era of globalization, namely the dominance of global culture over local values, social inequality and development disparities, as well as disinformation and polarization in the digital space. These challenges have the potential to weaken national identity, social solidarity, and public trust. To address these issues, several strategies are required, including strengthening education based on national values, improving digital and cultural literacy, ensuring equitable development, enhancing the quality of human resources, and reinforcing ethical communication and regulations in the digital sphere. Thus, national integration in the era of globalization requires collaborative efforts from the government, educational institutions, and society to maintain national unity. Strong national integration will serve as a foundation for addressing global challenges while enhancing national competitiveness at the international level.