Purpose – The research aims to determine the role and new findings from the internal and external environments in the value-driven business strategy model on university performance, with the partnership dimension as a mediating variable. Methodology – The research method uses a causality quantitative approach, with a purposive sampling technique of 125 respondents who are position holders at universities in West Java. The research data analysis technique uses Structural Equation Modeling (SEM) with SmartPLS software. Findings – The results of the study provide findings that the external environment and internal environment have a significant effect on value-driven business strategy. Partnership does not affect college performance, so value-driven business strategy significantly affects partnership. Value-driven business strategy significantly affects college performance; in the mediation dimension, the partnership does not mediate the relationship between value-driven business strategy and college performance. Value-driven business strategy does not mediate the relationship between the external environment and college performance. Finally, a value-driven business strategy can mediate the relationship between the internal environment and college performance. Originality – This study extends the Value-Driven Business Strategy Theory by adding new variables: the external and internal environments on the performance of higher Education institutions through value-based strategies, and a mediating variable, partnership, that connects value-based strategy to the performance of higher Education institutions. The external and internal environments are among the factors in improving the performance of higher Education institutions, and partnership is considered an important variable in value-based business strategies.