Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Indonesian Journal of Jamu
Lilik Sulastri
Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Pakuan University, Bogor, 16143, West Java
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
LC-HRMS Metabolite Profiling, Antioxidant, and α-Glucosidase Inhibitory Activities of Averrhoa bilimbi L. Fruit Extracts by Maceration and Ultrasound-Assisted Extraction Lilik Sulastri; Siti Nurul Habibah; Ema Hermawati; Rikkit Rikkit
Jurnal Jamu Indonesia Vol. 11 No. 4 (2026): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i4.535

Abstract

Bilimbi fruit (Averrhoa bilimbi L.) contains bioactive compounds with antioxidant and α-glucosidase inhibitory potential. This study compared 70% ethanolic extracts prepared by maceration and ultrasound-assisted extraction (UAE) in terms of yield, total phenolic content (TPC), total flavonoid content (TFC), DPPH radical-scavenging activity, α-glucosidase inhibition, and LC-HRMS metabolite profiles. Maceration produced a higher yield than UAE (16.23% vs. 11.16%), whereas TPC and TFC were comparable. UAE showed lower DPPH IC₅₀ (37.06 ± 0.27 vs. 51.59 ± 0.21 µg/mL) and α-glucosidase IC₅₀ (23.94 vs. 33.45 µg/mL) than maceration. LC-HRMS yielded 24 tentative or probable metabolite annotations, of which seven were selected for focused interpretation. Because each extraction method was performed once and analytical measurements were technical replicates, between-method differences are descriptive. LC-HRMS findings were qualitative and do not establish quantitative enrichment or compound-specific causality.
Co-Authors Ema Hermawati Rikkit Rikkit Siti Nurul Habibah