<![CDATA[Background: Biology learning at the high school level requires a solid grasp of concepts and strong learning interest for students to understand the material optimally—particularly the Nervous System topic, which is characterized by abstract and complex concepts. Learning interest is a crucial factor influencing student engagement in the learning process and academic achievement. This study aims to analyze the learning interest of Grade XI students regarding the Nervous System topic at HAS Sepakat Private High School and to identify differences in learning interest between classes XI-1 and XI-2. Methods: This study employed a descriptive quantitative approach. The sample consisted of 60 Grade XI Science students at HAS Sepakat Private High School, divided into two classes: XI-1 and XI-2. Data were collected through Likert-scale questionnaires, observation, and documentation. Data analysis involved descriptive statistics (total scores, means, standard deviations, and percentages) and inferential statistics (normality tests, homogeneity tests, One-Way ANOVA, and Welch's test) using SPSS. Results: The results showed that the total learning interest score reached 3,419 out of an ideal score of 4,500 (75.98%), placing it in the high category. However, the indicators for active engagement and curiosity showed relatively lower achievement compared to other indicators. The mean learning interest score for class XI-1 was 38.39 (standard deviation: 1.927), while for class XI-2, it was 37.45 (standard deviation: 4.356). The One-Way ANOVA yielded a significance value of 0.319, and Welch's test yielded a significance value of 0.326. Both values exceeded 0.05, indicating no significant difference in learning interest between students in class XI-1 and class XI-2. Conclusion: The learning interest of Grade XI students regarding the Nervous System topic at HAS Sepakat Private High School falls into the high category. Nevertheless, active engagement and curiosity still need to be enhanced to support a more optimal learning process. Furthermore, no significant difference in learning interest was found between students in classes XI-1 and XI-2.]]>
