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All Journal Jurnal Gizi dan Pangan Pharmacology and Clinical Pharmacy Research Jurnal Ilmiah Profesi Pendidikan
Anggraeni, Neni
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Education Health Professions Medicine & Pharmacology

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FABP4 and Metabolite Profile in Lipopolysaccharide-Induced Mice Model Treated with Moringa oleifera Ethanol Leaf Extract Hanifah, Cenia P.; Sulistiyorini, Ifa; Sumirat, Vanessa A.; Anggraeni, Neni; Putri, Mirasari; Ghozali, Mohammad; Syamsunarno, Mas Rizky A.A
Pharmacology and Clinical Pharmacy Research Vol 8, No 3 (2023)
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/pcpr.v8i3.50860

Abstract

Sepsis, a life-threatening organ dysfunction resulting from a dysregulated host response to infection, induces changes in blood cells and metabolic alterations. Fatty acid binding protein 4 (FABP4), a lipid chaperone predominantly expressed in adipose tissue, is modulated in sepsis and may contribute to metabolic and immunologic changes. Moringa oleifera (M. oleifera) leaf extract (MOLE) is known to modulate immune system activity, but its potential for treating acute inflammatory conditions like sepsis remains unclear. This study investigates the ability of MOLE to modulate metabolite and hematological profiles in lipopolysaccharide (LPS)-induced sepsis in mice. Thirty-five male Swiss Webster mice (Mus musculus) were divided into five groups, including healthy control pre-treated with 0.5% carboxymethyl cellulose (CMC), an LPS-induced negative control, an LPS-induced positive control treated with dexamethasone (DMX) 7mg/KgBW/day and two MOLE treatment groups with doses of 5.6 and 11.2 mg/20 gBW. Mice received MOLE pre-treatment for three days before LPS induction. Three hours post-LPS injection, the LPS-induced group exhibited leukopenia (1.4 [0.9-2.5] x109 cells/L) and a 68.3% increase in triglyceride levels. However, the MOLE-treated group showed improved erythrocyte levels compared to the positive control group; [(9.9(9.3-10.0) x1012 cell/L) vs (7.7(7.0-9.0) x1012 cells/L), p<0.05]. The study suggests that MOLE administration may positively impact sepsis conditions, particularly by enhancing RBC levels. Further research with an extended observation period is recommended to address limitations in metabolite level assessment.  
ASUPAN SENG, KADAR SERUM SENG, DAN STUNTING PADA ANAK SEKOLAH DI PESISIR SEMARANG Pramono, Adriyan; Panunggal, Binar; Anggraeni, Neni; Rahfiludin, Mohammad Zen
Jurnal Gizi dan Pangan Vol. 11 No. 1 (2016)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.401 KB) | DOI: 10.25182/jgp.2016.11.1.%p

Abstract

The purpose of this study is to determine prevalence of at risk inadequate intake of dietary zinc, and to analyze differences of zinc serum level between dietary zinc quintile and stunting status. A cross sectional study was conducted to 70 school children (9-12 years) selected by simple random sampling. Height was measured by stadiometer and weight was measured using calibrated digital weight-scale. Zinc serum level was analyzed by Atomic Absorbance Spectrophotometry (AAS) method, and dietary intake of zinc and iron was obtained using semi-quantitative Food Frequency Questionnaire (FFQ). Data were analyzed using Anova test. Seventy percent subjects were at risk inadequate intake of dietary zinc based on Estimated Average Requirement (EAR) cut off and zinc serum levels among all subjects in this study were <65 μg/dl. There were 47.1% stunting children found in this study. Mean zinc serum levels significantly differences between dietary zinc quintile (p=0.000) and between stunting status (p=0.000). At risk inadequate dietary zinc still contributed to zinc deficiency in coastal school children population. Zinc status was significantly different between stunted and normal children.Keywords: coastal area, dietary zinc, EAR, stunting, zinc serum levels 
Empowering Communities through Participatory Educational Planning: A Review of Strategies and Outcomes Nurhayati, Sri; Izzatillah, Pawwaz Najmi; Anindita, Tiaranissa; Silitonga, Desi; Sutisna, Ipin; Muttaqin, M. Zenal; Karimah, Yayu; Nurhikmatussolihah, Rahma; Pelitawati, Eka; Anggraeni, Neni; Silalahi, Rony; Fredy, Lim; Sukarso, Rita; Amalia, Zahrina; Nurlia, Yayang Siti; Ardioga, Mochamad
Jurnal Ilmiah Profesi Pendidikan Vol. 10 No. 3 (2025): Agustus
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jipp.v10i3.3454

Abstract

Participatory planning in community-based education is increasingly recognized as a critical strategy to advance equity, learner agency, and context-sensitive program development. This study systematically synthesizes empirical and theoretical literature to examine how participatory planning is conceptualized, implemented, and evaluated in diverse community education contexts. Using a systematic literature review, 35 peer-reviewed articles published between 2000 and 2025 were analyzed from Scopus database. Studies were selected based on defined inclusion criteria, and key data were thematically reviewed to identify patterns in participatory strategies, enabling conditions, and educational outcomes. The findings reveal that participatory planning enhances curricular relevance, democratic governance, and social inclusion, especially when embedded in authentic and culturally responsive processes. It aligns educational practices with community priorities, strengthens stakeholder collaboration, and fosters long-term program sustainability. However, its effectiveness is often constrained by structural challenges, including institutional rigidity, uneven power dynamics, and limited facilitator capacity. The review highlights that the success of participatory planning is context-dependent and relational, requiring deliberate adaptation and sustained institutional support. This study advances an integrative framework linking forms of participation with educational impact and contributes a cross-contextual synthesis to the literature. It affirms the potential of participatory planning to democratize education and calls for further research into digital innovations, long-term outcomes, and governance-sensitive implementation.
Co-Authors Adriyan Pramono Amalia, Zahrina Anindita, Tiaranissa Ardioga, Mochamad Binar Panunggal Fredy, Lim Hanifah, Cenia P. Izzatillah, Pawwaz Najmi Karimah, Yayu Mohammad Ghozali, Mohammad Mohammad Zen Rahfiludin Muttaqin, M. Zenal Nurhikmatussolihah, Rahma Nurlia, Yayang Siti Pelitawati, Eka Silalahi, Rony Silitonga, Desi Sri Nurhayati Sukarso, Rita Sulistiyorini, Ifa Sumirat, Vanessa A. Sutisna, Ipin Syamsunarno, Mas Rizky A.A