Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal JSFK (Jurnal Sains Farmasi & Klinis)
Elsa Nurita
Department of Pharmacy, Faculty of Pharmacy, Abdurrab University
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Nanoemulgel Based Delivery of Pometia pinnata Leaf Extract as a Potent Antioxidant Larysa Fernenda; Kony Putriani; Asiska Permata Dewi; Elsa Nurita; Bintang Indragiri; Yandi Syukri
JSFK (Jurnal Sains Farmasi & Klinis) Vol 13 No 02 (2026): J Sains Farm Klin 13(2), August 2026
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.13.02.101-107.2026

Abstract

This study aimed to formulate and evaluate a nanoemulgel containing ethanol extract of Pometia pinnata leaf as a topical antioxidant preparation. The extract was obtained through maceration using 96% ethanol, then formulated into a nanoemulsion and incorporated into a gel base containing Carbopol 940 at concentrations of 0.5%, 1%, and 2%. The evaluations included organoleptic test, homogeneity, pH, spreadability, viscosity, physical stability, and antioxidant activity, using the DPPH method with IC₅₀ as the parameter. The results showed that all formulations met acceptable physical criteria.  The pH values ranged from 4.86 to 5.49, while the spreadability ranged from 4.81 to 5.95 cm. The best formulation was the nanoemulgel containing 2% Carbopol, which showed an IC₅₀ value of 88.78 ppm, indicating strong antioxidant activity. These findings suggest that the Pometia pinnata ethanolic leaf extract nanoemulgel has promising potential as a topical antioxidant formulation for preventing premature skin aging.
Co-Authors Asiska Permata Dewi Bintang Indragiri Kony Putriani Larysa Fernenda Yandi Syukri