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p-Index From 2021 - 2026
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All Journal Majalah Obat Tradisional
Rollando Rollando
Ma Chung University, Malang, East Java, 65151
Health Professions Medicine & Pharmacology Public Health

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Antibacterial, Antioxidant and Anticancer Evaluation of Ginger Water Extract from Mempawah Regency Dodi Iskandar; Donor Utomo Muhammad Susilo; Y. Erning Indrastuti; Rollando Rollando; Narsih Narsih; Adi Hermawansyah; Zaenal Muttaqin; Muhammad Hilmi Afthoni
Majalah Obat Tradisional Vol 31, No 2 (2026)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.103310

Abstract

This study evaluated the antibacterial, antioxidant, and anticancer activities of aqueous ginger extract (Zingiber officinale) obtained from Mempawah Regency. The extraction process was carried out by boiling ginger in distilled water until a concentrated paste was obtained. From 2 kg of raw material, the extraction yielded 197 g of extract (9.85%), which was subsequently used for further bioactivity testing. Antibacterial activity was assessed against Escherichia coli (E. coli) using the disc diffusion method, resulting in an average inhibition zone of 4.17 ± 0.29 mm. Antioxidant activity was determined using the Ferric Reducing Antioxidant Power (FRAP) method, showing a value of 33.74 mg Ascorbic Acid Equivalent per gram of extract (mg AAE/g). Meanwhile, anticancer testing against MCF-7 cells yielded an IC₅₀ value of 4,654 µg/mL.
Co-Authors Adi Hermawansyah Dodi Iskandar Donor Utomo Muhammad Susilo Muhammad Hilmi Afthoni Narsih Narsih Y. Erning Indrastuti Zaenal Muttaqin