Introduction: Pesantren have long been recognised as centres of Islamic education; however, their role as institutions for developing Islamic entrepreneurship remains insufficiently conceptualised. Existing Islamic entrepreneurship models are predominantly derived from social entrepreneurship frameworks and often overlook the ethical and spiritual dimensions embedded in Islamic legal principles. This study aims to develop a comprehensive Santripreneurship model by integrating Maqashid al-Shariah and social capital within the pesantren context. Methods: This study employed a qualitative conceptual approach through an integrated literature review of Islamic economics, Islamic entrepreneurship, Maqashid al-Shariah, and social capital theory to construct a theoretically grounded Santripreneurship model. Results: The findings demonstrate that Maqashid al-Shariah functions as the ethical foundation guiding entrepreneurial behaviour, while bonding, bridging, and linking social capital serve as relational mechanisms that strengthen entrepreneurial capacity. Furthermore, pesantren culture provides the institutional identity shaping entrepreneurial values and practices. The proposed framework generates four theoretical propositions linking the internalisation of Maqashid al-Shariah, social capital, and sustainable economic empowerment, which can be empirically examined in future studies. Conclusion: The study concludes that Santripreneurship represents a value-oriented model of Islamic entrepreneurship that extends beyond profit generation by promoting ethical entrepreneurship, community empowerment, and institutional resilience. Future research should empirically validate the proposed model across diverse pesantren settings and examine its implications for Islamic microfinance and community-based economic development