Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Advances in Healthcare Research
Emma Jayanti Besan
Universitas Muhammadiyah Kudus, Kudus, Indonesia
Health Professions

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Formulation and Antibacterial Activity Testing of Face Mist Made from Red Betel Leaf (Piper Crocatum Ruiz and Pav.) Ethanol Extract Against Propionibacterium Acnes Ira Anggraeni; Riana Putri Rahmawati; Emma Jayanti Besan
Advances in Healthcare Research Vol. 3 No. 2 (2025)
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.571

Abstract

Purpose: This study aimed to formulate and evaluate the antibacterial activity of face mist containing ethanol extract of red betel leaf (Piper crocatum Ruiz & Pav.) against Propionibacterium acnes, with the hypothesis that higher extract concentrations enhance antibacterial efficacy. Research Method: A quantitative experimental design was conducted using three formulations with extract concentrations of 15%, 25%, and 35%, alongside positive (clindamycin 300 mg) and negative (base face mist) controls. Samples were obtained from Kayen Village, Pati Regency, Indonesia. Physical evaluations included organoleptic, homogeneity, pH, and spreadability tests, while antibacterial activity was assessed using the disc diffusion method. Data were analyzed with Shapiro–Wilk, Levene’s, One-Way ANOVA, and LSD Post Hoc tests. Results and Discussion: All formulations met physical quality standards. Antibacterial testing showed inhibition zones of 7.57 mm (moderate) for 15%, 10.67 mm (strong) for 25%, and 13.47 mm (strong) for 35%, with higher concentrations producing greater inhibition. Positive control exhibited a 37.60 mm (very strong) inhibition zone, while the negative control showed no activity. Implications: Red betel leaf extract demonstrates potential as a natural antibacterial ingredient in acne treatment formulations. The 35% concentration was optimal but still less effective than clindamycin. Future research should focus on optimizing formulation stability, enhancing sensory appeal, and exploring synergistic combinations to improve efficacy.
Formulation and Antioxidant Activity Test of Micellar Water Extracted from Mangosteen Fruit Peel (Garcinia mangostana L.) Using the DPPH Method with Variations in the Concentration of PEG-7 Glyceryl Cocoate as a Surfactant Yunita Andriyani; Muhammad Nurul Fadel; Emma Jayanti Besan
Advances in Healthcare Research Vol. 3 No. 2 (2025)
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.588

Abstract

Purpose: This study aims to determine the effect of PEG-7 glyceryl cocoate at concentrations of F1 0.2%, F2 0.4%, and F3 0.6% on the physical stability and cleaning power of micellar water preparations containing mangosteen peel extract. The best formulation was then tested for its antioxidant activity using the DPPH method. Research Method: This study used a laboratory experimental method. The variations in PEG-7 glyceryl cocoate concentration used in the micellar water extract of mangosteen peel were F1 (0.2%), F2 (0.4%), F3 (0.6%), and negative control F0 (0%). Evaluations were conducted on physical stability tests (organoleptic, pH, homogeneity, and viscosity) and cleaning power. The best micellar water formulation was then tested for antioxidant activity using the DPPH method. The test results were analyzed using a One-Way ANOVA test. Results and Discussion: The results of testing F3 micellar water, with the highest concentration of PEG-7 glyceryl cocoate, demonstrated that it was the best formula and exhibited the best cleaning ability. The results of the analysis using one-way ANOVA showed a p-value of < 0.05. The antioxidant activity of F3 was determined to have an IC50 of 103.81 μg/ml, which falls within the moderate category. Implications: The results of this study indicate that PEG-7 glyceryl cocoate at a concentration of 0.6% can be used as a surfactant in micellar water preparations of mangosteen peel extract. Further research is needed to determine the long-term stability of the preparation.
Co-Authors Ira Anggraeni Muhammad Nurul Fadel Riana Putri Rahmawati Yunita Andriyani