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Muhammad Nurul Fadel
Universitas Muhammadiyah Kudus, Kudus, Indonesia
Health Professions

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Evaluation of The Drug Storage System at The Welahan II Health Center Based on The Minister of Health Regulation No. 74 of 2016 Dea Safira; Zaenal Fanani; Muhammad Nurul Fadel
Advances in Healthcare Research Vol. 4 No. 1 (2026)
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v4i1.716

Abstract

Purpose: This study aimed to evaluate the compliance of the drug storage system at Welahan II Community Health Center with the standards set in the Minister of Health Regulation No. 74 of 2016. It was hypothesized that the storage system would exhibit high compliance, although several aspects of the physical infrastructure might still require improvement. Research Method: This study used a quantitative descriptive-evaluative design with a cross-sectional approach. Data were collected in February 2026 through direct observation using checklists, structured interviews, and documentation in the pharmaceutical warehouse of Welahan II Community Health Center. The evaluation covered spatial arrangement, stock preparation, separation of special drugs, observation of drug quality, and recording on stock cards. Data were analyzed descriptively by calculating the percentage of compliance with regulatory indicators. Results and Discussion: The overall average compliance was 93%, categorized as very good. Perfect compliance (100%) was achieved in special drug separation, physical quality observation, and stock card recording. Stock preparation reached 90%, while spatial arrangement had the lowest score (75%) due to limited warehouse space and non-standard room layout. Implications: The findings indicate that strong administrative and technical discipline can compensate for infrastructure limitations in maintaining drug quality and patient safety. Further studies should assess the effect of storage compliance on service efficiency and medication error prevention.
Formulation Research and Antibacterial Activity Test of Face Mist Preparation from Ethanol Extract of Papaya Leaves (Carica Papaya L.) Against Propionibacterium Acnes Aulia Nur Mustaanah; Muhammad Nurul Fadel; Muhamad Khudzaifi
Advances in Healthcare Research Vol. 3 No. 2 (2025)
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.559

Abstract

Purpose: The purpose of this study was to formulate a face mist preparation containing ethanol extract of papaya leaves (Carica papaya L.) at concentrations of 10%, 15%, and 20%, and to evaluate its antibacterial activity against Propionibacterium acnes, a primary acne-causing bacterium. Research Method: This study employed a laboratory-based experimental design with a post-test-only control group. Data were collected through experimental observations. The face mist was formulated with three extract concentrations (F1: 10%, F2: 15%, and F3: 20%), with a face mist base as the negative control and clindamycin as the positive control. The preparations underwent organoleptic, pH, homogeneity, and spreadability tests. Antibacterial activity was evaluated using the disc diffusion method, and the data were analyzed using One-Way ANOVA with a significance level of p < 0.005. Results and Discussion: The formulations met the physical property standards, showing a brownish-green color, liquid consistency, and a characteristic papaya leaf aroma. All samples were homogeneous, with pH values ranging from 5.08 to 5.16, and spreadability between 5.33 and 5.75 cm. The highest antibacterial activity was observed in F3 (20%) with an average inhibition zone of 16.3 mm. Implications: The findings suggest that papaya leaf ethanol extract is a promising natural ingredient for face mist formulations with antibacterial properties, offering potential as an alternative acne treatment product.
Formulation and Antioxidant Activity Test of Micellar Water Extracted from Mangosteen Fruit Peel (Garcinia mangostana L.) Using the DPPH Method with Variations in the Concentration of PEG-7 Glyceryl Cocoate as a Surfactant Yunita Andriyani; Muhammad Nurul Fadel; Emma Jayanti Besan
Advances in Healthcare Research Vol. 3 No. 2 (2025)
Publisher : Yayasan Pendidikan Bukhari Dwi Muslim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60079/ahr.v3i2.588

Abstract

Purpose: This study aims to determine the effect of PEG-7 glyceryl cocoate at concentrations of F1 0.2%, F2 0.4%, and F3 0.6% on the physical stability and cleaning power of micellar water preparations containing mangosteen peel extract. The best formulation was then tested for its antioxidant activity using the DPPH method. Research Method: This study used a laboratory experimental method. The variations in PEG-7 glyceryl cocoate concentration used in the micellar water extract of mangosteen peel were F1 (0.2%), F2 (0.4%), F3 (0.6%), and negative control F0 (0%). Evaluations were conducted on physical stability tests (organoleptic, pH, homogeneity, and viscosity) and cleaning power. The best micellar water formulation was then tested for antioxidant activity using the DPPH method. The test results were analyzed using a One-Way ANOVA test. Results and Discussion: The results of testing F3 micellar water, with the highest concentration of PEG-7 glyceryl cocoate, demonstrated that it was the best formula and exhibited the best cleaning ability. The results of the analysis using one-way ANOVA showed a p-value of < 0.05. The antioxidant activity of F3 was determined to have an IC50 of 103.81 μg/ml, which falls within the moderate category. Implications: The results of this study indicate that PEG-7 glyceryl cocoate at a concentration of 0.6% can be used as a surfactant in micellar water preparations of mangosteen peel extract. Further research is needed to determine the long-term stability of the preparation.
Co-Authors Aulia Nur Mustaanah Dea Safira Emma Jayanti Besan Muhamad Khudzaifi Yunita Andriyani Zaenal Fanani