This study aims to examine the impact and influence of the social boycott move-ment against pro-Israel products on the growth of Micro, Small, and Medium En-terprises (MSMEs) in Makassar City from the perspective of Islamic economics. The background of this research is based on the increasing social and religious awareness of Muslim communities regarding the humanitarian crisis in Palestine, which has led to changes in consumer behavior through the boycott of products perceived to be affiliated with Israel. This research employed a quantitative approach using a survey method. Data were collected through the distribution of questionnaires to 113 MSME actors in Rappocini and Tamalate Districts, Makassar City, determined using the Slovin formula. Data analysis was conducted using simple linear regression with the as-sistance of SPSS to examine the effect of the social boycott movement against pro-Israel products (X) on MSME growth (Y).The results indicate that the social boycott movement against pro-Israel products has a positive and significant effect on the growth of MSMEs in Makassar City. This finding suggests that increased public participation in the boycott move-ment encourages a shift in consumer preferences toward local products, resulting in increased sales, customer numbers, and business sustainability for MSMEs. From the perspective of Islamic economics, this phenomenon reflects the imple-mentation of values such as justice, public welfare (maslahah), and social respon-sibility in economic activities.