Background: Performance is the result of a certain process carried out by all components of the organization on certain resources used. In addition, performance affects organizational goals. This study aims to analyze the influence of training, education level, and gender on performance in health workers. Subject and Method: This study is a systematic study and meta-analysis, with the following PICO : Population = Health workers, Intervention = Training, Higher education level, Female, Comparison = No training, Low education level, Male, Outcome = Performance. The articles used in this study were obtained from several databases, including Google Scholar, PubMed, and ScienceDirect which were published from 2014 to 2024. These articles were collected over a period of 4 weeks. The keywords used by the researcher in searching the database include Community Health Workers OR CHW AND Job Performance OR Work Performance AND Training AND Education Level AND Gender OR Sex. The articles included in this study are full-text articles with a cross sectional study design. Articles are collected using PRISMA flow diagrams. Articles are analyzed using the Review Manager 5.3 application. Results: A total of 14 articles were reviewed in this meta-analysis study from Malaysia, China, India, Ethiopia, Uganda, Cameroon and Ghana. Studies show that healthcare workers with training (aOR=2.94; CI 95%= 1.33 to 6.46; p= 0.007), higher education level (aOR=2.16; CI 95%= 1.62 to 2.88; p<0.001) had a significant influence on performance. Meanwhile, women (aOR=0.92; CI 95%= 0.57 to 1.49; p=0.75) had an insignificant effect on performance.Conclusion: Training and higher education levels can significantly improve performance in health workers, and statistically insignificant performance differences between men and women, women have the possibility of performing well.