This study aims to describe the development process, determine product feasibility, and evaluate the effectiveness of a Science Student Worksheet (LKM) integrated with Eco-Entrepreneurship Project-Based Learning (EEPjBL) on ecosystem topics for junior high school students. The study was conducted using the ADDIE development model, which includes Analysis, Design, Development, Implementation, and Evaluation stages. The subjects in this study were seventh-grade students of SMP Negeri 28 Batanghari. Data collection instruments consisted of expert validation questionnaires, teacher and student response questionnaires, cognitive pretest-posttest, and non-test questionnaires measuring environmental care attitudes and entrepreneurial spirits. The results showed that: the development process produced an EEPjBL-based LKM prototype utilizing local oil palm waste; then the product feasibility achieved very valid and practical categories, based on material expert validation (95.00%), media expert validation (82.50%), science teacher response (86.25%), and student field trial response (71.63%); and the product was proven effective in significantly improving students’ conceptual understanding (Wilcoxon test Z = -4.487, p = 0.000; paired t-test t = -6.538, p = 0.000; Cohen’s d = 1.21; and average N-gain = 0.5026 in the medium category). Furthermore, students achieved excellent scores in environmental care attitude (89.25%) and entrepreneurial spirit (89.00%). Thus, the developed LKM is feasible and effective to be implemented in contextual and sustainable science learning.