The One Village One Product (OVOP) approach is a community-based economic development strategy that encourages villages to optimize local resources through the development of distinctive and competitive products. This study aims to analyze the implementation of the OVOP concept in Tambakrejo Village and its contribution to the development of local economy-based Micro, Small, and Medium Enterprises (MSMEs). This research employs a qualitative descriptive approach, with data collected through observation, interviews with MSME actors and village stakeholders, and documentation of local economic activities. The findings indicate that Tambakrejo Village has considerable potential for developing local products based on its available natural resources, community skills, and entrepreneurial activities. The implementation of OVOP can strengthen MSME capacity through product development, improvement of product quality and packaging, utilization of digital marketing, expansion of market access, and enhancement of community participation. However, several challenges remain, including limited managerial capacity, access to financing, technology adoption, product standardization, and sustainable marketing strategies. Therefore, the successful implementation of OVOP requires stronger collaboration among the village government, MSME actors, community groups, financial institutions, and other supporting stakeholders. The OVOP approach not only has the potential to increase MSME competitiveness but also serves as an instrument for strengthening local economic independence and creating sustainable village-based economic growth.