According to the Indonesian Health Survey (SKI) conducted in 2024, dental and oral health problems among individuals aged ≥ 3 years accounted for 56.9% of the total survey population. Geographically, coastal locations are typically situated far from urban centers, and the economic conditions of the less affluent population, coupled with diverse social conditions, result in varied psychosocial conditions in these areas. This situation was also observed on Kodingareng Island in the Sangkarrang Subdistrict of Makassar City. This study aimed to analyze the relationship between psychosocial factors and oral hygiene among the coastal community of Kodingareng Island. This study used an analytical observational design employing a cross-sectional approach. Oral hygiene data were collected from intraoral examinations and recorded on examination forms, while psychosocial aspects were measured using a psychosocial questionnaire that assessed stress levels, social support, psychological well-being, and dental anxiety. The results of this study showed a p-value of 0.02 for the relationship between stress levels and social support, where p < 0.05 indicates a significant association between the two. The p-value for the relationship between dental anxiety and psychological well-being was 0.02 (p < 0.05), indicating a significant association between the two variables. All psychosocial aspects examined, including stress levels, social support, psychological well-being, and dental anxiety, were significantly associated with oral hygiene status (OHI-S) among the coastal community of Kodingareng Island.