<![CDATA[АBSTRACT Exposure to 1800 MHz cellular phone electromagnetic radiation can induce oxidative stress causing decreased Leydig cell count and testosterone levels. This study aimed to evaluate the protective effect of Carbon Fibre Reinforced Polymer (CFRP) shielding with variations of 1, 2, and 4 layers on Leydig cell count and testosterone levels in male Wistar rats exposed to 1800 MHz electromagnetic radiation. This experimental study used 30 male Wistar rats divided into 5 groups: normal, control, and CFRP treatment with 1, 2, 4 layers. Radiation exposure was conducted 2 hours per day for 30 days. Analysis used hematoxylin-eosin staining and ELISA. The control group showed significant decrease in Leydig cell count (16.33 cells) and testosterone levels (8546.5 ng/ml) compared to normal group. CFRP shielding with 2 and 4 layers significantly increased Leydig cell count (p0.05), while only 4 layers significantly increased testosterone levels (p0.05). CFRP proved effective as electromagnetic radiation protection through reflection loss, absorption loss, and multiple reflections mechanisms, with optimal effectiveness at 4-layer configuration. Keywords: Carbon Fibre Reinforced Polymer, Cellular Phone, Electromagnetic Radiation, Leydig Cells, Testosterone Levels. ABSTRAK Paparan radiasi elektromagnetik telepon selular 1800 MHz dapat menginduksi stres oksidatif yang menyebabkan penurunan jumlah sel Leydig dan kadar testosteron. Penelitian ini bertujuan mengevaluasi efek protektif shielding Carbon Fibre Reinforced Polymer (CFRP) dengan variasi 1, 2, dan 4 lapisan terhadap jumlah sel Leydig dan kadar testosteron pada tikus Wistar jantan yang terpapar radiasi elektromagnetik 1800 MHz. Penelitian eksperimental menggunakan 30 tikus Wistar jantan yang dibagi menjadi 5 kelompok: normal, kontrol, dan perlakuan CFRP 1, 2, 4 lapisan. Paparan radiasi dilakukan 2 jam per hari selama 30 hari. Analisis menggunakan pewarnaan hematoksilin-eosin dan ELISA. Kelompok kontrol menunjukkan penurunan signifikan jumlah sel Leydig (16,33 sel) dan kadar testosteron (8546,5 ng/ml) dibandingkan kelompok normal. Shielding CFRP 2 dan 4 lapisan meningkatkan jumlah sel Leydig secara signifikan (p0,05), sedangkan hanya 4 lapisan yang meningkatkan kadar testosteron secara signifikan (p0,05). CFRP terbukti efektif sebagai proteksi radiasi elektromagnetik melalui mekanisme reflection loss, absorption loss, dan multiple reflections, dengan efektivitas optimal pada konfigurasi 4 lapisan. Kata Kunci: Carbon Fibre Reinforced Polymer, Kadar Testosteron, Radiasi Elektromagnetik, Sel Leydig, Telepon Selular.]]>
