<![CDATA[Background: Chronic kidney disease (CKD) is a progressive and irreversible decline in kidney function requiring hemodialysis. Depression is the most common psychological comorbidity in hemodialysis patients, significantly impairing quality of life, treatment adherence, and clinical outcomes. Palliative care offers a holistic approach to addressing physical, psychological, social, and spiritual suffering in this population. Objective: To describe the level of depression among CKD patients undergoing hemodialysis therapy within a palliative care context. Methods: A quantitative descriptive study with a cross-sectional approach included 50 respondents selected through simple random sampling. Depression was assessed using the Beck Depression Inventory-II (BDI-II). Data were analyzed univariately using IBM SPSS Statistics, and frequencies and percentages were reported. Results: The majority of respondents experienced severe depression (27/50; 54.0%), followed by moderate depression (9/50; 18.0%), and minimal/no depression (14/50; 28.0%). No respondents experienced mild depression. Most participants were male (33/50; 66.0%), aged 20–35 years (28/50; 56.0%), had senior high school education (31/50; 62.0%), and were unmarried (34/50; 68.0%). The most common duration of hemodialysis was 1 month (20/50; 40.0%), and hypertension was the most common comorbidity (18/50; 36.0%). Conclusion: Severe depression predominated among CKD patients undergoing hemodialysis within palliative care. These findings underscore the urgency of routine psychological assessment and integration of palliative care principles, including depression screening, emotional support, and interdisciplinary collaboration, into nephrology nursing practice.]]>
