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All Journal Journal of Psychiatry Psychology and Behavioral Research (JPPBR)
Primastuti Arganist, Maharani
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Humanities Education Medicine & Pharmacology Nursing Public Health

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THE POTENTIAL ROLE OF TRANSCRANIAL MAGNETIC STIMULATION IN PREVENTING COGNITIVE IMPAIRMENT AMONG INDIVIDUALS AT RISK FOR ALZHEIMER'S DISEASE: A NARRATIVE REVIEW Wirasto, Ronny Tri; Primastuti Arganist, Maharani
Journal of Psychiatry Psychology and Behavioral Research Vol. 7 No. 2 (2026): Emerging Perspectives in Mental Health: From Clinical Challenges to Innovative
Publisher : Departemen Psikiatri Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Alzheimer’s disease (AD) is the most common form of dementia and is on the rise worldwide. Individuals with Mild Cognitive Impairment (MCI) are at high risk of developing AD and experiencing cognitive impairment. Current pharmacological therapies remain limited in preventing disease progression. Transcranial Magnetic Stimulation (TMS) is a non-pharmacological intervention with the potential to prevent the progression of MCI to AD. Methods: This study uses a narrative review method by accessing relevant articles through electronic databases such as PubMed, ScienceDirect, and Google Scholar, focusing on publications from 2016 to 2026. The authors applied inclusion and exclusion criteria to select the articles. Results: TMS has been shown to improve overall cognitive function, memory, and executive function in individuals with MCI and those at risk for AD. Discuss: TMS improves neuroplasticity and functional brain connectivity by modulating cortical activity and increasing the expression of brain-derived neurotrophic factor (BDNF), which may slow the progression of neurodegenerative processes. Conclusion: TMS has the potential to serve as a nonpharmacological intervention that can delay cognitive decline and the progression from MCI to Alzheimer’s disease.
Co-Authors Wirasto, Ronny Tri