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All Journal Jurnal SainHealth
Yenny Puspa Rini
D4 TEKNOLOGI LABORATORIUM MEDIS
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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Hubungan Kadar Glukosa Darah, Albumin dan Kreatinin Pada Penyembuhan Luka Pasien Diabetes Melitus: Association Between Blood Glucose, Albumin, and Creatinine Levels and Wound Healing in Patients With Diabetes Mellitus Adinda Hartini Ningtyas; Yenny Puspa Rini; Novi Ersanto; Esti Rizkiana Pratiwi
Jurnal SainHealth Vol. 10 No. 2 (2026): September 2026
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v10i2.17469.131-138

Abstract

Diabetes Mellitus (DM) is a degenerative disease with a continuously increasing prevalence and a risk of chronic complications in the form of wounds or diabetic ulcers that are difficult to heal. Beyond blood glucose levels, nutritional status reflected by serum albumin and creatinine levels are also thought to influence tissue regeneration, since chronic hyperglycemia, hypoalbuminemia, and the accumulation of uremic toxins can inhibit angiogenesis, fibroblast proliferation, and local immune responses at the wound site. This study aimed to analyze the effect of blood glucose, serum albumin and creatinine levels on the rate of wound healing in patients with Diabetes Mellitus at Klinik Sahabat Sehat Lamongan. The study employed a quantitative analytical observational design with a cross-sectional approach, involving 44 respondents selected through purposive sampling, with laboratory data and wound observations analyzed using bivariate chi-square tests and multivariate analysis. The results showed that all Three variables were significantly associated with the rate of wound healing (p = 0.000), and simultaneously had a significant effect, with blood glucose level being the most dominant factor.
Co-Authors Adinda Hartini Ningtyas Esti Rizkiana Pratiwi Novi Ersanto